NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1958772849|ref|XP_038964675|]
View 

cilia- and flagella-associated protein 100 isoform X10 [Rattus norvegicus]

Protein Classification

DUF4200 domain-containing protein( domain architecture ID 11227509)

DUF4200 domain-containing protein such as cilia- and flagella-associated protein (CFAP), which is a coiled-coil domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DUF4200 pfam13863
Domain of unknown function (DUF4200); This family is found in eukaryotes. It is a coiled-coil ...
 152-270 7.60e-28

Domain of unknown function (DUF4200); This family is found in eukaryotes. It is a coiled-coil domain of unknwon function.


:

Pssm-ID: 464003 [Multi-domain]  Cd Length: 119  Bit Score: 105.34  E-value: 7.60e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958772849 152 YMEKKRSMFLLQYALAMKHNEIQRLEMLATREENRLERAEKFLEKDASLFDEFLRENDRNSVQAMRLAEKETKIKTEKIV 231
Cdd:pfam13863   1 LLEKKREMFLVQLALDAKREEIERLEELLKQREEELEKKEQELKEDLIKFDKFLKENDAKRRRALKKAEEETKLKKEKEK 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1958772849 232 EIRELTAQITSIKSEISKFEDTLKHYKIYKDFLYKVSPK 270
Cdd:pfam13863  81 EIKKLTAQIEELKSEISKLEEKLEEYKPYEDFLEKVVPK 119
 
Name Accession Description Interval E-value
DUF4200 pfam13863
Domain of unknown function (DUF4200); This family is found in eukaryotes. It is a coiled-coil ...
 152-270 7.60e-28

Domain of unknown function (DUF4200); This family is found in eukaryotes. It is a coiled-coil domain of unknwon function.


Pssm-ID: 464003 [Multi-domain]  Cd Length: 119  Bit Score: 105.34  E-value: 7.60e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958772849 152 YMEKKRSMFLLQYALAMKHNEIQRLEMLATREENRLERAEKFLEKDASLFDEFLRENDRNSVQAMRLAEKETKIKTEKIV 231
Cdd:pfam13863   1 LLEKKREMFLVQLALDAKREEIERLEELLKQREEELEKKEQELKEDLIKFDKFLKENDAKRRRALKKAEEETKLKKEKEK 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1958772849 232 EIRELTAQITSIKSEISKFEDTLKHYKIYKDFLYKVSPK 270
Cdd:pfam13863  81 EIKKLTAQIEELKSEISKLEEKLEEYKPYEDFLEKVVPK 119
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 64-255 3.54e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.27  E-value: 3.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958772849   64 FLLREQERN---------QAIAEREQKKILRVHQKMTYASKVLAKHTSLRRELQLEDEMEQQQLNAEAEEmnefrdnnaw 134
Cdd:TIGR02168  193 DILNELERQlkslerqaeKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAEL---------- 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958772849  135 kmtvtREKKKEHETLNDYM-EKKRSMFLLQYALAMKHNEIQRLEMLATREENRLERAEKFLEKDASLFDEFLRENDRnsv 213
Cdd:TIGR02168  263 -----QELEEKLEELRLEVsELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDE--- 334

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1958772849  214 QAMRLAEKETKIKtekiveirELTAQITSIKSEISKFEDTLK 255
Cdd:TIGR02168  335 LAEELAELEEKLE--------ELKEELESLEAELEELEAELE 368
 
Name Accession Description Interval E-value
DUF4200 pfam13863
Domain of unknown function (DUF4200); This family is found in eukaryotes. It is a coiled-coil ...
 152-270 7.60e-28

Domain of unknown function (DUF4200); This family is found in eukaryotes. It is a coiled-coil domain of unknwon function.


Pssm-ID: 464003 [Multi-domain]  Cd Length: 119  Bit Score: 105.34  E-value: 7.60e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958772849 152 YMEKKRSMFLLQYALAMKHNEIQRLEMLATREENRLERAEKFLEKDASLFDEFLRENDRNSVQAMRLAEKETKIKTEKIV 231
Cdd:pfam13863   1 LLEKKREMFLVQLALDAKREEIERLEELLKQREEELEKKEQELKEDLIKFDKFLKENDAKRRRALKKAEEETKLKKEKEK 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1958772849 232 EIRELTAQITSIKSEISKFEDTLKHYKIYKDFLYKVSPK 270
Cdd:pfam13863  81 EIKKLTAQIEELKSEISKLEEKLEEYKPYEDFLEKVVPK 119
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 64-255 3.54e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.27  E-value: 3.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958772849   64 FLLREQERN---------QAIAEREQKKILRVHQKMTYASKVLAKHTSLRRELQLEDEMEQQQLNAEAEEmnefrdnnaw 134
Cdd:TIGR02168  193 DILNELERQlkslerqaeKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAEL---------- 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958772849  135 kmtvtREKKKEHETLNDYM-EKKRSMFLLQYALAMKHNEIQRLEMLATREENRLERAEKFLEKDASLFDEFLRENDRnsv 213
Cdd:TIGR02168  263 -----QELEEKLEELRLEVsELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDE--- 334

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1958772849  214 QAMRLAEKETKIKtekiveirELTAQITSIKSEISKFEDTLK 255
Cdd:TIGR02168  335 LAEELAELEEKLE--------ELKEELESLEAELEELEAELE 368
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH