protein O-mannosyl-transferase TMTC1 isoform X6 [Rattus norvegicus]
DUF1736 domain-containing protein( domain architecture ID 10552345)
DUF1736 domain-containing protein
List of domain hits
Name | Accession | Description | Interval | E-value | ||
TMTC_DUF1736 | pfam08409 | Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ... |
351-425 | 4.72e-35 | ||
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3. : Pssm-ID: 462468 Cd Length: 75 Bit Score: 126.10 E-value: 4.72e-35
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Name | Accession | Description | Interval | E-value | ||
TMTC_DUF1736 | pfam08409 | Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ... |
351-425 | 4.72e-35 | ||
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3. Pssm-ID: 462468 Cd Length: 75 Bit Score: 126.10 E-value: 4.72e-35
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Name | Accession | Description | Interval | E-value | ||
TMTC_DUF1736 | pfam08409 | Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in ... |
351-425 | 4.72e-35 | ||
Protein O-mannosyl-transferase TMTC, DUF1736; This domain of unknown function is found in O-mannosyl -transferases TMTC1-4, and constitutes a loop between TM7 and TM8 located in the ER lumen that contains a small hydrophobic, but not membrane-embedded helix. This loop is critical for catalysis and binding of ligands, especially the lipid-linked sugar moiety. TMTCs transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases acting primarily on the cadherin superfamily; each member has distinct roles in decorating the cadherin domains with O-linked mannose glycans at specific regions. These proteins also act as O-mannosyl-transferase on other proteins such as PDIA3. Pssm-ID: 462468 Cd Length: 75 Bit Score: 126.10 E-value: 4.72e-35
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Blast search parameters | ||||
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