3OX3: X-ray Structural study of quinone reductase II inhibition by compounds with micromolar to nanomolar range IC50 values

PDB ID: 3OX3Download
MMDB ID: 90806
PDB Deposition Date: 2010/9/21
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3OX3: dimeric; determined by author and by software (PISA)
Molecular Components in 3OX3
Label Count Molecule
Proteins (2 molecules)
2
Ribosyldihydronicotinamide Dehydrogenase [quinone]
(Gene symbol: NQO2)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
ZINC IONZINC ION
2
2
FLAVIN-ADENINE DINUCLEOTIDEFLAVIN-ADENINE DINUCLEOTIDE
3
2
N-[2-(2-methoxy-1H-dipyrido[2,3-a:3',2'-e]pyrrolizin-11-yl)ethyl]furan-2-carboxamideN-[2-(2-methoxy-1H-dipyrido[2,3-a:3',2'-e]pyrrolizin-11-yl)ethyl]furan-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303