Conserved Protein Domain Family
ATF7IP_BD

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pfam16788: ATF7IP_BD 
ATF-interacting protein binding domain
ATF7IP-BD is a short conserved region of activating transcription factor 7-interacting protein 1 found in higher eukaryotes. This domain appears to bind several key proteins such as TFIIE-alpha and TFIIE-beta as well the transcriptional regulator Sp1 which are part of the transcriptional machinery.
Statistics
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PSSM-Id: 465271
Aligned: 24 rows
Threshold Bit Score: 134.804
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_019658737  293 KENVKRMKTSE------QINENICVALEKQTALLKQVKHLIRQEIYSINYKLFDNKLKELTERIGKTQCRNKHEAIADEL 366 
XP_014349033  524 SSEVKRRRFLGeey-eaELQVKITARGDMNKKLEKVVQRLLEEKLTALQCTEFDKSLADLRTRVEKLECKK-HEAVLSNL 601 
XP_016853654  404 SVHSKRCRNTGeey-eaELEVKITTRGNVQQNIEKIIHRFLEEKFSVLQCAVFDKTLADLKTRVDKVECSKRHKTAVTEL 482 
XP_012424565  392 NVHSKHRRYMGedy-eaEVQVKITARKDVDLKLQKIIQRLLEEKLTALQCAVFDKTLADLKTRMEKVECNKRHKTVLTEM 470 
XP_003202388  378 SVHSKRRRYVGeedyeaEFQVKITARRDVDQKLEKVIQRVLEEKLAALQCAVFDKTLADLKMRIEKVECNKRHKTVLTEL 457 
EOB06704      392 SVHSKRRRYVGedy-eaELQVKITARRDVDQKLQKVIQRLLEEKLAALQCAVFDKTLADLKMRIEKIECNKRHKTVLTEL 470 
XP_007503754  414 NVQSKRRRYLGeey-eaELQVKITARGDINQKLQKVVQRLLEEKLSALQCAVFDKTLADLKMRVEKIECNKRHKTVLTEL 492 
CAB45135       20 NVQSKRRRYMEeey-eaEFQVKITAKGDINQKLQKVIQWLLEEKLCALQCAVFDKTLAELKTRVEKIECNKRHKTVLTEL 98  
2_pfamImport    1 KRELKRPKMQNhel-eaKLELKITAKAGAHPKLEKVVQQLVEQHLRALQLNIFDQHFKELKDRIDKIDCAAKHQTAVNTL 79  
XP_028910054  429 SIHSKRRRYVGeey-eaELQVKITAREDINQKLQKVVQRLLDEKLGALQCAVFDKALADLKTRVEKIECNKRHKTVLTEL 507  platypus
XP_019658737  367 FAKISKLQRRIKAVLQSQKN-----CL-EPNVLTSNTACKVTNSETVNLEKNPESVSSPDEGQTSVSSE---PSNPSAKA 437 
XP_014349033  602 QAKIARLIKRFGAAREDLKKsqehnAAvQPLSPVRAPNSNQ------QSYRSTNTVRHMLESKRSLDSTa--PLPTSSNS 673 
XP_016853654  483 QAKIARLTKRFGAAREDSKKkp-----eNPHSPEK-AVSDTGGINN-AQFRNAGTVRQMLESKRNVGEStttTFQSPVNT 555 
XP_012424565  471 QAKIARLTKRVGAAKEDLKKrqenvAN-APVSPGKAAPDTANGNNA--TYRNAGTVRQMLESKRNVGEStpaTFQAPVNP 547 
XP_003202388  458 QAKISRLTKRFGAAKEDMEEkqentPN-PSLSSGKAASSTANANN--LTYRNITTVRQMLESKRNVGDSkpaTLQAPVNP 534 
EOB06704      471 QAKVARLTKRFGAAKEDLKKrqenpPN-SPLSPVKAASDTVSTTNT--TYRNAGTVRQMLESKRSVGVStttTFQASLST 547 
XP_007503754  493 QAKIARLTKRFGAAKEDLKKrqenpPN-PPVSPGKSTANEVVSINN-LTYRNAGTVRQMLESKRNIGENtpsPFQAPVNA 570 
CAB45135       99 QAKIARLTKRFEAAKEDLKKrhehpPN-PPVSPGK-TVNDVNSNNN-MSYRNAGTVRQMLESKRNVSESappSFQTPVNT 175 
2_pfamImport   80 QSKITRLAKKFGEANQELENkkkqeDL--QVVAAAVTAKTTTTASSPQVQRNSQCYLKILNKATvp-----aTAAVP--A 150 
XP_028910054  508 QAKIARLTKRFGAAKEDLKKrqqnpPN-PPPSPGKCTSEAVGVNT--LTYRNAGTVRQMLESKRNVGENapaPFPVP--- 581  platypus
XP_019658737  438 SEKVNLSRDHSEAVSESN--DDVMLISVESPNLTTPITSNPTDTGKTtsgnsnNSNNSPGAETEVTAVEKK 506 
XP_014349033  674 VCGSSITSSQ-AVAGQPKppATVSSSSM-VPPILPPVAATATATAVV------GTSQPASSTTQPMSVSLQ 736 
XP_016853654  556 VSATTIIAPQTQSSGHTKpqTPVTSAPLTSGTLTTSVIPAPNTATVV------GTNQVAGGNTQSMSVSLQ 620 
XP_012424565  548 VPASSLAASPAVVSGHPKlqTPVSSTS----SLTTAVLPTANTATVV------GTNQVPTGSAPSVSVSLQ 608 
XP_003202388  535 APPSSLAAPQTPTSGHPKpqTPVTSSP-----LTTAVISTANTATVV------GTSQVPSGSTQPMSVSLQ 594 
EOB06704      548 VPASTFVAPQIPGSGHPKpqTPVTSSP-----LTTTVLSTANTAAVV------GTSQVPSGSTQQMSVSLQ 607 
XP_007503754  571 VSSASIATPQTAVSGQPKsqTPVTSGS-----LTASVLPAPTTAPVV------ASTQVSSGNSQP-TISLQ 629 
CAB45135      176 VSSTNLVTPPAVVSSQPKlqTPVTSGSLT----ATSVLPAPNTATVV------ATTQVPSGNPQP-TISLQ 235 
2_pfamImport  151 LAPVSTPAPPPAPAPVPVptSTAMVI-------QAPVLQLITSTSN-------AASPLPTALTSQNPTGTL 207 
XP_028910054  582 ------VNTASSTGPGPtqaagggqpkpqtpvtsasltasvlpapnaatvvattqvpsgsgqpvsvslqsl 646  platypus
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