Conserved Protein Domain Family
ALS2CR11

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pfam15729: ALS2CR11 
Amyotrophic lateral sclerosis 2 candidate 11
This family of proteins is found in eukaryotes. Proteins in this family are typically between 286 and 727 amino acids in length.
Statistics
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PSSM-Id: 464828
Aligned: 6 rows
Threshold Bit Score: 666.968
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_009236259   84 KGSDSEELEITQDTPNLVPFGDVVGCLGIHIKNCRHFTPK-ISVQHFaNLFIRISINKAAKCTKMCSLLSKN-----NEK 157 
NP_001019534  129 QGSQSDEMVVANQTQNLIPFGDVVGCLAIHIKSCRQFTQRfIAQQHF-NLFMRISVNHIVKCTKIRHLKAVN-----NEK 202 
NP_001071527   86 KGSENKAPEVTHEAPSLVPFGDVVGCLAIHIRNCKHFTPK-IISQHYsNLFIRISINNVVKCTKTCSLLSQN-----TEK 159 
XP_023618918   47 TGSESKEAKVTPNPENLVPFGDVAGCLAIHVKNCSHFTPK-IDVQHKnNFFIRISINNIVKYTKLCSLLPQNipfviNER 125  little brown bat
XP_012917800   90 KGSEIKEPEITPEVPTLVPFGDVVGCIAIHIKNCRHFTPK-ISLQHFkNLFIRISINNIVKCTKICSLASPN-----GEK 163  domestic ferret
XP_003405982   83 KEPENKELEVAPEMPTLVPFGDVVGCLAIHIKNCRYFTPKiILKPYYtNLFIRITINNVVKCTKMYTLLSKG-----NEK 157  African savan...
XP_009236259  158 NT----VIKFDEV--KYFSVQVPRRYDDERNNILLELIQ-YDNREKRAFLLGSVQIHLYEVIQKGCFIEEVQVLHRNIFV 230 
NP_001019534  203 NL----VLKFDEV--KYFSVQVPRRQDDERNYIYLELMQdAGDSEKLPYPLGNAESHLYEVIQKGCFTEVMQMMRRNTPI 276 
NP_001071527  160 DF----MITFDEV--KYFSVQVPRRQDDEKNNIRLELMQ-HDNTKKYLLLLGSVQVHLYEVIQKGCFTGELQVLNKNTFI 232 
XP_023618918  126 KT----LIKFDEV--KYFSVQVPRRQNDARNNIYLDLMQ-FDNKEKH-ILLGRVQVHLYEVIQKGCFTEEFQMLNENTFI 197  little brown bat
XP_012917800  164 YT----TVNFDDT--KYFSVQVPRRQDDERNNIYLELMQ-YRSTEKYPLLLGSVKVHLYDVIQKGCFIEEFEMLHKNLPI 236  domestic ferret
XP_003405982  158 NIiklmNCKFNAFfnTHFDIEVPRRPDDARNNIYLELME-YEDTEKYPVFLGSVQVHLYEVIQKGCFTEEFQILNKNTFV 236  African savan...
XP_009236259  231 CRLEVEFMFSYGNFGYGFSHQLKPLQKITEPSMFMNLAPPPERTDPVTKVITPQTVEYPAFLSPDLNVTVGTPAvq--sS 308 
NP_001019534  277 CRVEVEFMFSYGNFGYGFSHQLKPLQKVIEPSMFMKITPPPERTDPVTNIITPQRVEYPAFLSPEFNVNIGGPE-----T 351 
NP_001071527  233 CRVEVEFMFSYGNFGYGFSHQLKPLQKIIKPSMFMDIAPPPERTDPVTNVIIPQPIAYPAFLSPDLNVTVGVPAts--qS 310 
XP_023618918  198 CRMEVDFMFSYGNFGYGFSHQLKPLQKIVEPPMFMNIPPPPERTDPVTNIIIPQSIEYPAFLSPDLKVTVGMPPpe-dqP 276  little brown bat
XP_012917800  237 CKVAVEFMFSYGNFGYGFSHQLKPLQKINKPSMFMNIAPPPGRIDPVTNVITPQPIEYPAFLSPDLNVTVGAPAvv---p 313  domestic ferret
XP_003405982  237 CRVQVEFMFSYGNFGFGFSHQLKPLQKIIEPSMFMNIAPPPERTDPVSNVIVPQPVEYPAFLSPDLNVTVGKPSkasskS 316  African savan...
XP_009236259  309 NQPSVVRLEKLQQQPRERLEKMKKEYRNLNTWIDKANYLESILMPKLEHRDSE--------ETN---MDEASENLKSNQP 377 
NP_001019534  352 SQATVVQLEKLREKPRERLERMKEEYKSMNTWIEKADYLRNLINPKLLKKDSKgsvepsgsNSS---VLEELERTTHDIH 428 
NP_001071527  311 NQPSVVQLEKLQQQPRERLEKMKKEYRHLSTWAEKASYLEGLLTPGLEHKEPK--------ESN---INEIPESQL---- 375 
XP_023618918  277 NQPPAVRLEKLQQQPRERLEKMKKEYRDLPTWREKAAYLEGILNPKLGPSEPK--------GSD---T-Y---EVPESQF 341  little brown bat
XP_012917800  314 NQSSVVRLEKLQQQPRERLEKMKKEYRNLNTWIEKANYLEGILNPKMAHQELK--------ETDtekLLKSLREAESEvf 385  domestic ferret
XP_003405982  317 NQPSVVRLEKLQQPPRERLEKMKKEYRNLSTWIEKANYLGNILTPALEHKDTE--------RSN---TSDVLGSLTNDQL 385  African savan...
XP_009236259  378 EeelenivgvdiplvnEEAETTANELLDNDSEKGLTIPTLNQLDQDNSTADASKSDKSTP-------------------- 437 
NP_001019534  429 Y---------------RKSEAISNELVDYSDKEGRVIPVLKLLDQNYSEFSLPKSGDSTP-------------------- 473 
NP_001071527  376 EerptdtvtsgvslikEEAETIPSELLDNDDKKGLSLPTLNQSSKDDSSVVAPKTDMPSK-------------------- 435 
XP_023618918  342 EkkpedtvtsdishinKEVETIPTE------------------DGDNSKAFGPKRDEPAK-------------------- 383  little brown bat
XP_012917800  386 easd-------fpfvmEEAETVPSELLDNDDKKSLTLPTLNQSNQDNSRAVASESDESTKqtdestkqtdestkqtdgst 458  domestic ferret
XP_003405982  386 Kektqts---daplinEEVETVPKKLLDNKTLPTLTLPTLKLLHQDDLNAIPAKSDESEK-------------------- 442  African savan...
XP_009236259  438 --------Sp---tEVHSLCTISNQETIKAGRIPPL-DERQSESMPDRKMKNVFFPSEVKLKDNYPSILKADSSLSE 502 
NP_001019534  474 --------P-----EDVTLPPIHTLQIIEEDEMPRVpNTSELEDRPHEDRKSVIFSSDEELMPKHPSILKINPSLQE 537 
NP_001071527  436 --------E-----TDTPLSTIPRLSITEENQIPPL-EEHQQEAMPVKKMKNLFFLPEEKLKDRYPSLLKTDLHPSE 498 
XP_023618918  384 --------Q-----RAAPLFTIPNLTITEGNKMIPL-EEHQYEPVTDRKLLTKPLQPEGKLLDKHPSILKREsstse 446  little brown bat
XP_012917800  459 kqneptkqT--------PWPVIPILTITDQNQTSPL-EEYQSKAAPEGG-KNMFLTPDVKWKDRYPKLLKTDSSSSE 525  domestic ferret
XP_003405982  443 --------QtypppTDPPLFTIPTI---EEKKIPSS-DEHQ------------FSPPEVKLENRYPSPVKTDSSPPE 495  African savanna ...
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