Conserved Protein Domain Family
Uma2

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COG4636: Uma2 
Endonuclease, Uma2 family (restriction endonuclease fold) [General function prediction only]
Statistics
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PSSM-Id: 443674
Aligned: 640 rows
Threshold Bit Score: 57.6824
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_011318913   1 Mtq---alTKQVIFDEFID-Wl---PEnsEGRYELHDGVIVEMPKPSGKHSNVIGFLIEELFLSIIQI-GKrgiWTI-PR 71 
WP_014786229   1 MaataavsvPHIPVGEYLGsv--yrPD-----VDYVDGVLEERNVGEFDHADIQFAIMQVLEg-LRSE-GF---RSSmE- 67 
WP_013578439   1 Matp-----vlIPVEQYLSts--ydPD-----CDYIDGEVQERNRGERPHSLMQLALSAIFYSNRRAW-KV---LPMpE- 63 
WP_014785267   1 Mat----tPalMTMEQYLHts--fhPD-----VDFVDGDLQKRNLGEFDHGHLQGLLFAWFLQRMSST-RL---IPVvE- 64 
WP_013580560   1 Mats-----vlIPISEYLKtt--yrPD-----REYLDGEVVERHVGKWEHSRVQALLTGWFIQHERSW-NI---QTAtE- 63 
ADB41046       6 MpsrrkrpsAPQTVAEFEKwLsrkkT---DANYEFVRGRIIRKPSMKQEELFIARFLMRAFAK-TQLYqQGa--EMLsEG 79 
WP_013581354   1 MvastqiiPasISMEEYLHta--yhPD-----CDFVDGVLEKRNGGEYEHSNLQAALGAWFFNRgREW-GV---RVLtE- 68 
WP_011683677   1 Mstg-----tvVPLSEYLAts--yrPD-----CEYLDGRILERNVGEWDHSRLQMLMSRYLSNREKQW-GI---LVVvEQ 64 
WP_013581129   1 -------------MSEYLAts--yrPD-----CEYVDGELRGRNVGEWLHARSLALMASWIGGHENEW-NV---IGCiS- 55 
AEI50078       1 MiearetavLPKTLEEFMVwe--peD---GYKYEWNDGELIKFVGMNKTQVFIYEVLNQLFI--EKGFwKSg--TLIsEY 71 
WP_011318913  72 ESIVKPNSKSGYEPDIIVLDQEA-LSneprWERESIIEnpASVKLIVEVVStavassretrPthclTNWRDDYYKKRADY 150
WP_014786229  68 -TRVQVSATRFRVPDVCLLPKGW--K------KTQIIR--EAPRLCVEVLS----------P----RDTVMGMRRRCEDY 122
WP_013578439  64 -QRVQTSATRFRIPDVCLIAASD--P------ADPIVH--IPPILCVEIIS----------S----GQTLRHMQERTDDY 118
WP_014785267  65 -QRIRVSDRNVRICDVAVVSADA--P------REQVTM--SAPVICIEILS----------P----EDRIARAETVLADY 119
WP_013580560  64 -WRTQVSSTRVRIPDLVLVRSGA-QP--------EVLE--DAPLLVIEILS----------P----DDSYSDTQQRAEDY 117
ADB41046      80 DA-YVDAF-RKRIPDLAVFTDEQ-IRaaktGKRF-------MPPLAIEILS----------D----SESQNDVLEKVQDY 135
WP_013581354  69 -QRTRVGETRVRIADVCIIQRGGaIE--------RVRV--TPPLLCIEILS----------R----EDRITGTIRVLDDY 123
WP_011683677  65 R--VQVKATRFRVPDISVLTGPP--Pa------GPIIV--DPPFLCIDILS----------P----SDRMKEMQDRIDDY 118
WP_013581129  56 -LRVKTSSSRVRVPDLVVLRPRV-QP--------DILT--EPPLLVIEILS----------P----GDSYWDLQERSRDY 109
AEI50078      72 DV-QLTGI-QMRRPDIAYLSKEQ-IKrtkqGEDE-------IPEFLIEIIS----------G----SDNANKVEEKTAEY 127
WP_011318913 151 vrvasrrEEMGIPEYWIVDyaglggrafignPKQPTISVNYLIEGEYQVS---QFRQG-ERIQSVT-FPELDLT-VD--Q 222
WP_014786229 123 -------LRMGVPEVWIVD------------PQARVVFVMNAGG--FLERs----EGTlE-LQg----VPLHLD-IR--S 169
WP_013578439 119 -------LAMGVQQVWVLD------------PVRREAFIPSPSG--VLQPspdNL----N-VSg----TPIELS-WT--E 165
WP_014785267 120 -------RSMGVPNIWLID------------PFRRAAYFFDGS-G-LHHAldnTL----R-IAe----TELALE-MD--N 166
WP_013580560 118 -------LRMGVTTIWIID------------PSTRTGRVCSGSN--WMQRe--RL----E-VAg----TAIYVP-LD--R 162
ADB41046     136 -------FDAGVQLVWYIA------------PKQQKIYAYSSPDDI-KV-----YKEE-DVCSAAPvVPDFQFV-IR--D 186
WP_013581354 124 -------LAMGVKNLWVFD------------PVDRVAMTYGAK-G-LKIAegtRL----E-IAg----TPIYLDcLSflR 173
WP_011683677 119 -------LDFGVQYVWLLH------------PRTRRAFVYTRDA--VQEVkdgILGTA-D--------PAICVP-LS--E 165
WP_013581129 110 -------QAMGVETVWIVD------------PKTRSGRVCRGEE--WIGAe--RL----E-VAg----TPIYVE-LK--E 154
AEI50078     128 -------FKAGVKIMWLIY------------PDNKTVHVYTSRKQV-QI-----CTDD-DICSAKPiLPEFELS-VN--T 178
WP_011318913 223 IF 224
WP_014786229 170 IF 171
WP_013578439 166 IL 167
WP_014785267 167 LF 168
WP_013580560 163 VF 164
ADB41046     187 LF 188
WP_013581354 174 CW 175
WP_011683677 166 LE 167
WP_013581129 155 LF 156
AEI50078     179 LF 180
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