Conserved Protein Domain Family
HDNR

?
pfam15115: HDNR 
Domain of unknown function with conserved HDNR motif
This family of proteins is found in eukaryotes. Proteins in this family are typically between 117 and 219 amino acids in length. There is a conserved HDNR sequence motif. The function is not known.
Statistics
?
PSSM-Id: 464512
Aligned: 12 rows
Threshold Bit Score: 161.509
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
NP_001314851   2 SKGGkRYFNK--NKSVNWFVH--TGFSqteqTHHLCTSTGSALAHAVSQPLTPS-EQRYPKVF----INP--------EK 64 
XP_007962559   1 MTKG-RRFNPplDKDGRWFPH--IGLT----QKTSESNTRAMLKEPQSPHSPWQvEGKLPPIY----KVR--------EK 61 
XP_004751797   1 MAKG-RRFNPalDKDGRWFPQ--IGLT----QKTPESSTSAMLKEPHRPRSSRQvEGKLPPIY----KVR--------EK 61 
XP_002721284   1 MAKG-RRFNPplDEDGRWFPH--VGLM----QKTPESITRATLKEPLCAQAARQvEGRLPPIY----KVR--------EK 61 
ELK11837       1 MAKG-RRFNPplDKDGRWFPH--IGLT----QRAPESITRAALREPHSPQFSEQvQEKLPAIY----KVR--------EK 61 
Q6AXY6         1 MAKG-RRFNPslHKDGRWFTH--IGVI----EKIPESITSTSLKEIHCPYLSEQvEKRLPPIY----KIR--------EK 61  Norway rat
EEN59729       1 MPKG-RKFAPgnDCDGNWFRHrtRGYEtpkfQRHVDTSTGEMLTRPFSD-SSPSsQTNTPPKF----ANRldyvntqnAK 74 
EDO42577       1 MARSlYSNSAppDLTGSWYN---TGF-----HGHYRSRTRTDFAIPFRQRVKPAp----PQKF----LNY--------SK 56 
XP_015202451   1 MPKG-RNWNPcmDRDGEWFSH--LGFPpipfKREAATSTGCMLTQ-----ATKHpPNGVPERYlktsRTT--------EG 64 
XP_006143969   1 MAKG-RRFNPplDKDGKWFPH--IGLT----SKTPESITCAMLKESHSPCLSQQiERKLPPIY----KVR--------EK 61 
XP_003794159   1 MAKG-RRFNPplDKDGRWFPH--IGLT----QRTPESITTAMLKEPQCPHMSRQmEAKLPPIY----RIR--------EK 61 
XP_017393411   1 MAKG-RRFNPplDKDGRWFPH--IGLT----QKTPESITSATLKEPHRPHLSRQvEGKLPPIY----KVR--------EK 61  
NP_001314851  65 KTMGREYPLSMHDNRTALQQCI---DVYDQGSGRKKCL---D-ERRQH--NSHYSLRH-HHHGTPSLVtavKWEDSvYQK 134
XP_007962559  62 QAVNNQFPFSVHDNRHSLENSG---CYLDSGLGRKKIA---P-DKRQH--VSRNFNLW-ACDYVPSCL---DGFSN-NQI 127
XP_004751797  62 QAVNNNFPFSVHDNRHSLQSSG---CYLDSGLGRRKIS---P-EKRQH--ASRNFNLW-ACDHVPSCL---DGFSN-NQI 127
XP_002721284  62 QATNNSFPFSMHDNRHIFENSG---NYLDSGLGRKKIS---P-DKRQH--VSRNFNLW-ASDYVPSCL---DGFSN-NQI 127
ELK11837      62 QAANNSFPFSVHDNRHSFQNSG---YFFDSGMGRKKIS---P-EKRQH--VSRNFNLW-ACDYVPSCL---DGFSN-NQI 127
Q6AXY6        62 QAANKNFPFSVHDNRHCFENSG---YYFDSGLGRRKCT---P-DQKQH--ISRNFNLW-ACDYIPSNL---DGFSN-NQT 127 Norway rat
EEN59729      75 RYDQVN-PFSWHDNRNSFQDHG---EYFGHGLGKQSVV---PvEKSLH--YSNNYIRWtTREGSHT-----DNMSS-YAV 139
EDO42577      57 ERSNSH-LFSRHDNRNTHSDMGdleTFFGMGLGKRKYTrasAgIATQHtkSTQDLITW-RGNEN-------DSMVStYRT 127
XP_015202451  65 NTEKREYPFSVHDNRFALHRTS---EMFDVGLGRRKAL---D-GFSQH--SSHNFFLW-TQDAVPLVSvdgDGMSF-YHT 133
XP_006143969  62 QAVNNNFPFSMHDNRHSFENSG---YYLDSGLGRKKIS---P-DKRQH--ISRNFNLW-ACDYVPSCL---DGFSN-NQI 127
XP_003794159  62 QAVNNNFPFSVHDNRHSLGNTV---YYFDSGLGRKKIS---P-DRRQH--LSRNFNLW-ACDYVPSCV---DGFSN-NQI 127
XP_017393411  62 QAVNNHFPFSVHDNRHSLENYG---SYFDSGLGRKKIS---P-DKRQH--FSRNFNLW-ACDYVPSYL---DGFSN-NQI 127 
NP_001314851 135 DFL---------------PRQQIESREdkiRRRFPRDHSARsqvnaaaqadqcfmW---------------FGRDDAKQF 184
XP_007962559 128 SYV---------------HKEAVVVSS---FRRFPRCYKEI--------------Wntltflp-errytefLKKKPKVRF 174
XP_004751797 128 SYV---------------YREVVVLPI---FRRFPRHYNEI--------------Wksfkfip-rksytefLKKTPKVRF 174
XP_002721284 128 SYV---------------YKEARVDPW---FRRFPRCYAEV--------------Ws-------------tCRFIPERSY 162
ELK11837     128 SYV---------------CQEAMVVPI---FRRFPRRYNEI--------------Wstfkfip-qqsytetFKKHPKAKF 174
Q6AXY6       128 SYV---------------HKKAVVVSS---FRRFPRCYDER--------------Wiastq-----scpkfLGNQPNGEF 170 Norway rat
EEN59729     140 SFR---------------GDRDTESPT---RRRFPRTYSKPqqgrikl-dtattdWsn------------eSHRTPLQVM 188
EDO42577     128 HFEknpaitpiinetepvHIRSNLNL----RRRQLRAASAPptrq-------appLlawnepdeafyakpgVGLRPQSSF 196
XP_015202451 134 EYL---------------GCQETDRPS---FRRFPQNHAQMsrgsaaq-agrdlvW---------------FGRHDRTQH 179
XP_006143969 128 SYV---------------YKEAMVAPN---FRRFPRCYNEI--------------Qntfkivp-eqcctefLKKKPKVRF 174
XP_003794159 128 SYV---------------YKEAVVVPS---FRRFPRHYNEI--------------WrsfkfipeqrcytefLQKKPKVRF 175
XP_017393411 128 SYV---------------YKEAVVVSS---FRRFPRCYKEMwnt---------fvFlpers------ytefLKKKPKVRF 174 
NP_001314851 185 TP 186
XP_007962559 175 TI 176
XP_004751797 175 AI 176
XP_002721284 163 PK 164
ELK11837     175 TV 176
Q6AXY6       171 AV 172 Norway rat
EEN59729     189 AS 190
EDO42577     197 VR 198
XP_015202451 180 TP 181
XP_006143969 175 AI 176
XP_003794159 176 TI 177
XP_017393411 175 AI 176 
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap