GEO DataSets

Analysis of the hippocampus of immature animals up to 240 hours following kainite (KA) induced status epilepticus (SE). Unlike adults, KA-induced SE in immature animals causes neither cell death nor recurrent spontaneous seizures. Results provide insight into the molecular basis of these responses.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 age, 2 agent, 5 time sets

Platform:

GPL85

Series:

GSE4236

60 Samples

Download data: CEL

Analysis of lung alveolar type 2 cells from Sprague-Dawley males following 6 weeks of chronic ingestion of alcohol. The lungs can be irreversibly damaged from chronic alcohol consumption. Results provide insight into the molecular changes in the lung associated with chronic alcohol consumption.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 agent sets

Platform:

GPL85

Series:

GSE55243

7 Samples

Download data: CEL

Analysis of hippocampal CA1 from adrenalectomized F344 males maintained for 3 months with implanted corticosterone (CORT) pellets to produce low or intermediate (glucocorticoid receptor-activating) blood levels of CORT. Results provide insight into the effects of chronic CORT on the hippocampus.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 4 agent, 4 dose, 2 protocol sets

Platform:

GPL85

Series:

GSE37618

39 Samples

Download data: CEL

Analysis of L4 and L5 dorsal root ganglion (DRGs) up to 40 days post-injury in three distinct peripheral neuropathic pain models: spared nerve injury (SNI), chronic constriction injury (CCI), and spinal nerve ligation injury (SNL). Results provide insight into putative pain modulating genes.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 6 protocol, 5 time sets

Platform:

GPL85

Series:

GSE30691

56 Samples

Download data: CEL

Analysis of laser-microdissected airway epithelial cells from snap-frozen lung 0 and 2 days after lipopolysaccharide (LPS) exposure. Inhalation of LPS can lead to chronic lung diseases like cystic fibrosis and asthma. Results provide insight into inflammatory mediators modulated by LPS exposure.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 time sets

Platform:

GPL85

Series:

GSE36174

6 Samples

Download data: CEL, CHP, TXT

Analysis of superior cervical ganglia (SCG) cultured neurons treated with bone morphogenic protein-7 (BMP-7) for 6 or 24h. Addition of BMPs triggers these neurons to extend multiple dendrites. Results provide insight into molecular mechanisms underlying initial formation of primary dendrites.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 agent, 2 time sets

Platform:

GPL85

Series:

GSE28150

9 Samples

Download data: CEL

Analysis of pineal glands from Sprague-Dawley rats at mid-day (Zeitgeber time ZT7) or midnight (ZT19). Rats were kept on a 14:10 light-dark (LD) cycle. The pineal gland plays a vital role in vertebrate chronobiology. Results provide insight into night/day changes in pineal gene expression.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 time sets

Platform:

GPL85

Series:

GSE12341

6 Samples

Download data: CEL

Analysis of bladders from Sprague-Dawley females for up to 25 days following spinal cord injury (SCI). Bladder wall tissue compliance increases within 2 weeks after SCI in this animal model. Results provide insight into the molecular basis of the changes that the bladder undergoes after SCI.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 disease state, 4 time sets

Platform:

GPL85

Series:

GSE14096

4 Samples

Download data: CEL, CHP

Analysis of livers from males fed a high polyunsaturated diet containing 70% corn oil to induce the development of non-alcoholic steatohepatitis (NASH). In NASH, steatosis is accompanied by inflammation, necrosis, apoptosis, and fibrosis. Results provide insight into the pathogenesis of NASH.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 disease state sets

Platform:

GPL85

Series:

GSE8253

6 Samples

Download data: CEL, CHP, EXP

Analysis of maturing testes from animals suppressed for follicle stimulating hormone (FSH) activity from age 14 to 18 days. FSH activity suppressed by treatment with an antibody to FSH (FSHAb). Results provide insight into the role of FSH in Sertoli and male germ cell development.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL85

Series:

GSE10293

4 Samples

Download data: CEL

Analysis of myometria of ovariectomized animals following treatment with estradiol for 6 or 24 hours. Estrogen reduces the increased uterine sympathetic nerve density induced by ovariectomy. Results provide insight into the molecular mechanisms underlying estrogen-modulated sympathetic innervation.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent, 2 time sets

Platform:

GPL85

Series:

GSE9117

4 Samples

Download data: CEL, EXP

Analysis of thoracic aortas (TAs) of Fischer 344/Brown Norway F1 hybrids (F344xBN) at 3 to 28 months of age. Age is a risk factor for vascular disease. The TAs of F344xBN animals exhibit age-related pathologies. Results provide insight into the mechanisms underlying age-mediated vascular pathology.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 4 age sets

Platform:

GPL85

Series:

GSE7281

16 Samples

Download data: CEL, EXP

Analysis of ovaries with unassembled, primordial, and primary follicles. Abnormal primordial follicle development can cause pathologies such as premature ovarian failure. Results provide insight into molecular mechanisms underlying primordial follicle assembly and transition to primary follicles.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 3 development stage, 3 protocol sets

Platform:

GPL85

Series:

GSE9300

6 Samples

Download data: CEL

Analysis of brain at various time points up to 21 days following lateral fluid percussion-induced brain injury. Delayed cell death following trauma results in brain damage. Results provide insight into the mechanisms underlying brain damage after traumatic injury.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 protocol, 7 time sets

Platform:

GPL85

Series:

GSE2392

39 Samples

Download data: CEL

Analysis of various CNS regions of inbred alcohol-preferring and non-alcohol preferring animals that have not been exposed to alcohol. Results provide insight into the molecular basis of the difference in alcohol preference between the two strains.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 strain, 5 tissue sets

Platform:

GPL85

Series:

GSE4494

59 Samples

Download data: CEL

Analysis of lumbar dorsal root ganglia at various time points up to 50 days following peripheral nerve injury inflicted by either partial sciatic nerve ligation or chronic constriction. Results provide insight into the molecular mechanisms underlying neuropathic pain.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 3 protocol, 3 time sets

Platform:

GPL85

Series:

GSE2636

20 Samples

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Analysis of colons of soy or whey protein fed Sprague Dawley males 40 weeks after azoxymethane (AOM) injection to induce tumor formation. Lifetime consumption of soy or whey proteins reduces the incidence of AOM-induced colon tumors in rats.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 3 protocol sets

Platform:

GPL85

Series:

GSE6102

9 Samples

Download data: CEL, EXP

Analysis of L4 and L5 dorsal root ganglia (DRG) from animals 28 and 50 days following L5 spinal nerve ligation. L5 spinal nerve ligation is a model of neuropathic pain.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 protocol, 2 time, 3 tissue sets

Platform:

GPL85

Series:

GSE2884

12 Samples

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Analysis of normal livers, lungs, and mammary glands from Sprague Dawleys treated with targretin (TGR), 9-cis retinoic acid (9cRA), or 4-hydroxyphenylretinamide (4HPR). Results provide insight into the molecular basis of the varying chemopreventive anti-cancer effects of these agents.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 4 agent, 3 tissue sets

Platform:

GPL85

Series:

GSE3952

43 Samples

Download data

Analysis of ischemic cerebral cortices of ovariectomized animals on a regimen of 1 subcutaneous 17beta-estradiol pellet for 1 week. Ischemia was induced by middle cerebral artery occlusion. Results provide insight into the basis of estrogen's protective effect in experimental cerebral ischemia.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL85

Series:

GSE5315

4 Samples

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