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Links from GEO DataSets

Items: 5

1.

DNA damage repair in barley following double-strand breaks and its dependence on ATR

(Submitter supplied) Maintaining genome integrity presents a particular challenge for plants due to their sedentary lifestyle, which disables direct avoidance of unfavorable external conditions. Additionally, plants’ metabolic processes generate reactive molecules as by-products of e.g. photosynthesis, creating internal DNA-damaging conditions. Due to this, plants have developed a unique and strictly regulated web of DNA damage responses (DDR). more...
Organism:
Hordeum vulgare
Type:
Expression profiling by high throughput sequencing
Platform:
GPL29652
12 Samples
Download data: TXT, XLSX
Series
Accession:
GSE235051
ID:
200235051
2.

Genome-wide profiling of gamma-ray-responsive transcriptomes from Arabidopsis thaliana ecotype Col-0

(Submitter supplied) To analyze the genes of which their expressions are modulated by gamma irradiation, we performed the whole genome expression microarray profiling by comparing normal whole seedlings of Arabidopsis thaliana as control with those of gamma irradiated as test sample.
Organism:
Arabidopsis thaliana
Type:
Expression profiling by array
Platform:
GPL12621
10 Samples
Download data: TXT
Series
Accession:
GSE116647
ID:
200116647
3.

Transcriptome of Arabidopsis thaliana mem1-1 mutant

(Submitter supplied) Transcriptome of Arabidopsis thaliana mem1-1 mutant and Col-0 under normal and 200ppm MMS treatment conditions, respectively
Organism:
Arabidopsis thaliana
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13222
8 Samples
Download data: TXT
Series
Accession:
GSE181302
ID:
200181302
4.

Transcriptional response to zebularine and mitomycin C (MMC) in wild type and ATR deficient Arabidopsis thaliana plants

(Submitter supplied) Zebularine is a non-methylable cytidine analog that is used in epigenetic and cancer research. Its application has been shown to activate several transcriptionally silenced genetic elements; however, extent of this activation and other effects on the transcriptome are unknown. Here, we show that zebularine treatment induces preferentially genes associated with DNA damage repair response and this activation is strongly ATR-dependent. more...
Organism:
Arabidopsis thaliana
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17639
16 Samples
Download data: TXT
Series
Accession:
GSE63355
ID:
200063355
5.

Functionally-instructed modifiers of response to ATR inhibition in experimental glioma

(Submitter supplied) We investigated the influence of ATR inhibition by AZD6738 treatment in LN229 and LNZ308 glioma cells.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
24 Samples
Download data: TXT
Series
Accession:
GSE229614
ID:
200229614
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