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Full record GDS905

Pancreatic beta cell lines overexpressing wild type MODY genes or mutant HNF1b alleles

Analysis of gene expression in pancreatic beta cell line INS-1 overexpressing the transcription factors HNF1b, HNF4a2, HNF6, or mutant forms of HNF1b, which were introduced by FRT/FLP recombination. Dysfunction of these transcription factors cause maturity onset diabetes of the young (MODY).
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 5 cell line, 3 genotype/variation, 2 protocol sets
Platform:
GPL341
Series:
GSE6428
25 Samples
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