Saracatinib-sensitive versus -resistant, PIK3CA mutant colorectal cancer xenografts - - GEO DataSets

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Saracatinib-sensitive versus -resistant, PIK3CA mutant colorectal cancer xenografts

Analysis of patient-derived colorectal cancer (CRC) xenografts with a PIK3CA mutation with enhanced sensitivity to Src inhibitor saracatinib. Dysregulation of Src and PI3K (phosphoinositide 3-kinase) signaling pathways is common in CRC. Results provide insight into CRC model response to saracatinib.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:: GPL6244
Series:: GSE36006
4 Samples

Download data: CEL

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Accession:: GDS4383

ID:: 4383

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