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LOC102549158 sorting nexin-1-like [ Rattus norvegicus (Norway rat) ]

Gene ID: 102549158, updated on 9-Dec-2024

Summary

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Symbol
LOC102549158provided by RGD
Full Name
sorting nexin-1-likeprovided by RGD
Primary source
RGD:7624393
See related
AllianceGenome:RGD:7624393
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable phosphatidylinositol binding activity; protein dimerization activity; and signaling receptor binding activity. Predicted to be involved in several processes, including early endosome to Golgi transport; lamellipodium morphogenesis; and receptor internalization. Predicted to be located in several cellular components, including early endosome membrane; lamellipodium; and lysosome. Predicted to be part of retromer, tubulation complex. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See LOC102549158 in Genome Data Viewer
Location:
11q11
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (40899005..40900744)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (27412769..27414504)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (28056151..28057886)

Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene NADH:ubiquinone oxidoreductase subunit A7, pseudogene 1 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene BTB domain and CNC homolog 1 Neighboring gene glutamate ionotropic receptor kainate type subunit 1 Neighboring gene uncharacterized LOC108352301 Neighboring gene claudin 17

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables epidermal growth factor receptor binding IEA
Inferred from Electronic Annotation
more info
  
enables insulin receptor binding IEA
Inferred from Electronic Annotation
more info
  
enables leptin receptor binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
  
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables transferrin receptor binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in early endosome to Golgi transport IEA
Inferred from Electronic Annotation
more info
  
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in lamellipodium morphogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in receptor internalization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in early endosome membrane IEA
Inferred from Electronic Annotation
more info
  
located_in lamellipodium IEA
Inferred from Electronic Annotation
more info
  
located_in lysosome IEA
Inferred from Electronic Annotation
more info
  
part_of retromer, tubulation complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
sorting nexin-1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086029.1 Reference GRCr8

    Range
    40899005..40900744
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039088768.2 → XP_038944696.1  sorting nexin-1-like

    UniProtKB/TrEMBL
    A0A8L2QBU0
    Conserved Domains (2) summary
    cd07281
    Location:64 → 187
    PX_SNX1; The phosphoinositide binding Phox Homology domain of Sorting Nexin 1
    cd07665
    Location:205 → 438
    BAR_SNX1; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 1
Nucleotide Protein Strain
Heading Accession and Version

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Molecular Biology Databases
Research Materials