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carB carbamoyl-phosphate synthase large subunit [ Methanosarcina acetivorans C2A ]

Gene ID: 1474031, updated on 22-Oct-2024

Summary

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Gene symbol
carB
Gene description
carbamoyl-phosphate synthase large subunit
Locus tag
MA_RS11130
Gene type
protein coding
Organism
Methanosarcina acetivorans C2A (strain: C2A, type-material: type strain of Methanosarcina acetivorans)
Lineage
Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina
Old locus tag
MA2143; MA_2143
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Genomic context

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Sequence:
NC_003552.1 (2649918..2653130, complement)

NC_003552.1Genomic Context describing neighboring genes Neighboring gene ATP-dependent endonuclease Neighboring gene UvrD-helicase domain-containing protein Neighboring gene argininosuccinate synthase Neighboring gene glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit Neighboring gene glycine betaine/L-proline ABC transporter ATP-binding protein Neighboring gene proline/glycine betaine ABC transporter permease

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003552.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Selective inactivation of the glutamine binding site of Escherichia coli carbamyl phosphate synthetase by 2-amino-4-oxo-5-chloropentanoic acid. Khedouri E, et al. Biochemistry, 1966 Nov. PMID 5339592
  2. Reversible dissociation of the monomer of glutamine-dependent carbamyl phosphate synthetase into catalytically active heavy and light subunits. Trotta PP, et al. J Biol Chem, 1974 Jan 25. PMID 4358555
  3. Inactivation of the amidotransferase activity of carbamoyl phosphate synthetase by the antibiotic acivicin. Miles BW, et al. J Biol Chem, 2002 Feb 8. PMID 11729189
  4. Long-range allosteric transitions in carbamoyl phosphate synthetase. Thoden JB, et al. Protein Sci, 2004 Sep. PMID 15322282, Free PMC Article
  5. The structure of carbamoyl phosphate synthetase determined to 2.1 A resolution. Thoden JB, et al. Acta Crystallogr D Biol Crystallogr, 1999 Jan. PMID 10089390

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
carbamoyl-phosphate synthase large subunit
WP_011022129.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003552.1 Reference assembly

    Range
    2649918..2653130 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_011022129.1 carbamoyl-phosphate synthase large subunit [Methanosarcina acetivorans]

    See identical proteins and their annotated locations for WP_011022129.1

    UniProtKB/Swiss-Prot
    Q8TNY4
    UniProtKB/TrEMBL
    A0A832SHA2
    Conserved Domains (1) summary
    PRK05294
    Location:1 → 1065
    carB; carbamoyl-phosphate synthase large subunit
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8TNY4.1

Gene LinkOut

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Molecular Biology Databases