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Rnf17 ring finger protein 17 [ Rattus norvegicus (Norway rat) ]

Gene ID: 305908, updated on 4-Jan-2025

Summary

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Official Symbol
Rnf17provided by RGD
Official Full Name
ring finger protein 17provided by RGD
Primary source
RGD:1310486
See related
EnsemblRapid:ENSRNOG00000008059 AllianceGenome:RGD:1310486
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable identical protein binding activity. Predicted to act upstream of or within spermatid development. Predicted to be located in cytoplasm. Orthologous to human RNF17 (ring finger protein 17). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Restricted expression toward (RPKM 55.4) See more
Orthologs
human mouse all
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Genomic context

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See Rnf17 in Genome Data Viewer
Location:
15p12
Exon count:
38
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (34603448..34741658)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (30487899..30626024)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (36609348..36744750)

Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene granzyme B Neighboring gene ATPase H+/K+ transporting non-gastric alpha2 subunit Neighboring gene TM2 domain-containing protein 1 pseudogene Neighboring gene centrosome assembly and centriole elongation protein Neighboring gene poly (ADP-ribose) polymerase family, member 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. RNF17, a component of the mammalian germ cell nuage, is essential for spermiogenesis. Pan J, et al. Development, 2005 Sep. PMID 16093322, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within spermatid development ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
RING finger protein 17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191685.1 → NP_001178614.1  RING finger protein 17

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000015
    UniProtKB/TrEMBL
    A0A8I6GJ74, D3ZLP2
    Related
    ENSRNOP00000090862.2, ENSRNOT00000096665.2
    Conserved Domains (4) summary
    cd04508
    Location:755 → 801
    TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
    pfam00567
    Location:1196 → 1312
    TUDOR; Tudor domain
    cl22851
    Location:30 → 72
    PHD_SF; PHD finger superfamily
    cl23765
    Location:137 → 242
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086033.1 Reference GRCr8

    Range
    34603448..34741658
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039093305.2 → XP_038949233.1  RING finger protein 17 isoform X1

    UniProtKB/TrEMBL
    A0A8I6GJ74
    Related
    ENSRNOP00000010795.6, ENSRNOT00000010795.9
    Conserved Domains (7) summary
    smart00502
    Location:137 → 242
    BBC; B-Box C-terminal domain
    cd20414
    Location:490 → 566
    Tudor_TDRD4_rpt1; first Tudor domain found in Tudor domain-containing protein 4 (TDRD4) and similar proteins
    cd20415
    Location:728 → 823
    Tudor_TDRD4_rpt2; second Tudor domain found in Tudor domain-containing protein 4 (TDRD4) and similar proteins
    cd20416
    Location:968 → 1049
    Tudor_TDRD4_rpt3; third Tudor domain found in Tudor domain-containing protein 4 (TDRD4) and similar proteins
    cd20417
    Location:1247 → 1314
    Tudor_TDRD4_rpt4; fourth Tudor domain found in Tudor domain-containing protein 4 (TDRD4) and similar proteins
    cd20418
    Location:1504 → 1608
    Tudor_TDRD4_rpt5; fifth Tudor domain found in Tudor domain-containing protein 4 (TDRD4) and similar proteins
    cl22851
    Location:30 → 72
    PHD_SF; PHD finger superfamily

  2. XM_039093306.2 → XP_038949234.1  RING finger protein 17 isoform X2

    Conserved Domains (5) summary
    smart00502
    Location:137 → 242
    BBC; B-Box C-terminal domain
    cd20414
    Location:490 → 566
    Tudor_TDRD4_rpt1; first Tudor domain found in Tudor domain-containing protein 4 (TDRD4) and similar proteins
    cd20415
    Location:728 → 823
    Tudor_TDRD4_rpt2; second Tudor domain found in Tudor domain-containing protein 4 (TDRD4) and similar proteins
    cd20416
    Location:968 → 1049
    Tudor_TDRD4_rpt3; third Tudor domain found in Tudor domain-containing protein 4 (TDRD4) and similar proteins
    cl22851
    Location:30 → 72
    PHD_SF; PHD finger superfamily
Nucleotide Protein Strain
Heading Accession and Version

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