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Tmem114 transmembrane protein 114 [ Rattus norvegicus (Norway rat) ]

Gene ID: 501675, updated on 9-Dec-2024

Summary

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Official Symbol
Tmem114provided by RGD
Official Full Name
transmembrane protein 114provided by RGD
Primary source
RGD:1560593
See related
EnsemblRapid:ENSRNOG00000002768 AllianceGenome:RGD:1560593
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1560593
Summary
Predicted to be located in apicolateral plasma membrane. Predicted to be active in apical plasma membrane. Orthologous to human TMEM114 (transmembrane protein 114). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Brain (RPKM 3.1) and Testes (RPKM 1.2) See more
Orthologs
human mouse all
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Genomic context

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See Tmem114 in Genome Data Viewer
Location:
10q12
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (7676380..7691883)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (7168998..7185251)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (7279920..7295452)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120095024 Neighboring gene ribosomal protein L35A like 9 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene uncharacterized LOC102546970

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The cataract-associated protein TMEM114, and TMEM235, are glycosylated transmembrane proteins that are distinct from claudin family members. Maher GJ, et al. FEBS Lett, 2011 Jul 21. PMID 21689651
  2. Predicted expansion of the claudin multigene family. Mineta K, et al. FEBS Lett, 2011 Feb 18. PMID 21276448
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
is_active_in apical plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in apical plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in apicolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
transmembrane protein 114

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134638.1 → NP_001128110.1  transmembrane protein 114

    See identical proteins and their annotated locations for NP_001128110.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474017
    UniProtKB/TrEMBL
    A6K4M5, D3Z9M6
    Related
    ENSRNOP00000003749.3, ENSRNOT00000003749.6
    Conserved Domains (1) summary
    cl21598
    Location:20 → 206
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    7676380..7691883
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039086654.2 → XP_038942582.1  transmembrane protein 114 isoform X1

    Conserved Domains (1) summary
    cl21598
    Location:2 → 106
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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