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Cd209e CD209e molecule [ Rattus norvegicus (Norway rat) ]

Gene ID: 501797, updated on 9-Dec-2024

Summary

Official Symbol
Cd209eprovided by RGD
Official Full Name
CD209e moleculeprovided by RGD
Primary source
RGD:1563333
See related
EnsemblRapid:ENSRNOG00000028803 AllianceGenome:RGD:1563333
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1563333
Summary
Predicted to enable D-mannose binding activity and pattern recognition receptor activity. Predicted to be involved in immune response. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in Coronavirus infectious disease; aspergillosis; dengue disease (multiple); human immunodeficiency virus infectious disease (multiple); and tuberculosis (multiple). Orthologous to human CD209 (CD209 molecule). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Spleen (RPKM 20.1), Thymus (RPKM 2.4) and 1 other tissue See more
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Genomic context

See Cd209e in Genome Data Viewer
Location:
12p12
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (6661179..6666634, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (1862104..1868735, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (2381378..2387960, complement)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene C-type lectin domain family 4, member G Neighboring gene CD209a molecule Neighboring gene CD209d molecule Neighboring gene C-type lectin domain family 4 member M

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables D-mannose binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables pattern recognition receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
CD209 antigen-like protein E
Names
CD209e antigen

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001192005.1NP_001178934.1  CD209 antigen-like protein E

    See identical proteins and their annotated locations for NP_001178934.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000012
    UniProtKB/TrEMBL
    A6KQ42, D3ZCF3
    Related
    ENSRNOP00000029615.3, ENSRNOT00000031997.6
    Conserved Domains (1) summary
    cd03590
    Location:77199
    CLECT_DC-SIGN_like; C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    6661179..6666634 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)