Lrit3 leucine-rich repeat, Ig-like and transmembrane domains 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Lrit3provided by RGD
Official Full Name: leucine-rich repeat, Ig-like and transmembrane domains 3provided by RGD
Primary source: RGD:1559637
See related: EnsemblRapid:ENSRNOG00000061097 AllianceGenome:RGD:1559637
Gene type: protein coding
RefSeq status: MODEL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1559637
Summary: Predicted to be involved in regulation of fibroblast growth factor receptor signaling pathway. Predicted to act upstream of or within several processes, including synapse assembly involved in innervation; synaptic signaling; and visual perception. Predicted to be located in membrane and synapse. Predicted to be active in cell tip and dendrite. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1F. Orthologous to human LRIT3 (leucine rich repeat, Ig-like and transmembrane domains 3). [provided by Alliance of Genome Resources, Jan 2025]
Expression: Biased expression in Kidney (RPKM 4.9) and Brain (RPKM 0.6) See more
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (221011458..221034568, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (218337215..218360318, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (235213017..235232894, complement)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Submit: New GeneRIF Correction

Process	Evidence Code	Pubs
acts_upstream_of_or_within gene expression	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within protein localization	ISO Inferred from Sequence Orthology more info
involved_in regulation of fibroblast growth factor receptor signaling pathway	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within response to light stimulus	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within synapse assembly involved in innervation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within synaptic signaling	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within visual perception	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cell tip	ISO Inferred from Sequence Orthology more info
is_active_in dendrite	ISO Inferred from Sequence Orthology more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in synapse	IEA Inferred from Electronic Annotation more info

Preferred Names: leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3

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The following sections contain reference sequences that belong to a specific genome build. Explain