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Dynap dynactin associated protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 680077, updated on 9-Dec-2024

Summary

Official Symbol
Dynapprovided by RGD
Official Full Name
dynactin associated proteinprovided by RGD
Primary source
RGD:1596811
See related
EnsemblRapid:ENSRNOG00000063474 AllianceGenome:RGD:1596811
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Dynapl
Summary
Predicted to be involved in several processes, including activation of protein kinase B activity; cellular response to ergosterol; and positive regulation of cell population proliferation. Predicted to be located in Golgi apparatus and plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
Expression
Restricted expression toward (RPKM 33.6) See more
Orthologs
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Genomic context

See Dynap in Genome Data Viewer
Location:
18q12.1
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (66160548..66227999, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (63885164..63909464, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (68773133..68838901, complement)

Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene cytoskeleton-associated protein 2, pseudogene 2 Neighboring gene dynactin associated protein-like 1 Neighboring gene uncharacterized LOC134482986 Neighboring gene similar to human chromosome 18 open reading frame 54

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in activation of protein kinase B activity ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to ergosterol ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cell population proliferation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of cell population proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
dynactin-associated protein
Names
dynactin associated protein like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001400775.1NP_001387704.1  dynactin-associated protein

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000018
    UniProtKB/TrEMBL
    A0A8I6AJT4
    Related
    ENSRNOP00000088925.1, ENSRNOT00000097602.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086036.1 Reference GRCr8

    Range
    66160548..66227999 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063277584.1XP_063133654.1  dynactin-associated protein isoform X1

  2. XM_039097303.2XP_038953231.1  dynactin-associated protein isoform X2

  3. XM_063277585.1XP_063133655.1  dynactin-associated protein isoform X1

  4. XM_063277583.1XP_063133653.1  dynactin-associated protein isoform X1