Utf1 undifferentiated embryonic cell transcription factor 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Utf1provided by RGD
Official Full Name: undifferentiated embryonic cell transcription factor 1provided by RGD
Primary source: RGD:1589375
See related: EnsemblRapid:ENSRNOG00000050207 AllianceGenome:RGD:1589375
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable HMG box domain binding activity; TBP-class protein binding activity; and transcription coactivator activity. Predicted to be involved in male gonad development and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human UTF1 (undifferentiated embryonic cell transcription factor 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 1.7), Thymus (RPKM 1.3) and 2 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q41

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (204169954..204171080)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (194740339..194741465)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (212281237..212282363)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables HMG box domain binding	ISO Inferred from Sequence Orthology more info
enables TBP-class protein binding	ISO Inferred from Sequence Orthology more info
enables transcription coactivator activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in male gonad development	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: undifferentiated embryonic cell transcription factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001131032.2 → NP_001124504.2 undifferentiated embryonic cell transcription factor 1

Status: PROVISIONAL

Source sequence(s)

JAXUCZ010000001

UniProtKB/TrEMBL

A6HXD1, B3FIB5, M0RAP1

Related

ENSRNOP00000066594.1, ENSRNOT00000075049.3

Conserved Domains (2) summary

PHA03247
Location:5 → 265

PHA03247; large tegument protein UL36; Provisional

pfam13837
Location:79 → 126

Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain