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    Isoc2a isochorismatase domain containing 2A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 684270, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Isoc2aprovided by RGD
    Official Full Name
    isochorismatase domain containing 2Aprovided by RGD
    Primary source
    RGD:1592677
    See related
    EnsemblRapid:ENSRNOG00000050348 AllianceGenome:RGD:1592677
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Orthologous to human ISOC2 (isochorismatase domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 207.2), Heart (RPKM 149.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Isoc2a in Genome Data Viewer
    Location:
    1q12
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (77967751..77986002, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (68938916..68957179, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (72491667..72509433, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 628 Neighboring gene similar to human chromosome 19 open reading frame 85 Neighboring gene ATPase H+ transporting V0 subunit C, pseudogene 2 Neighboring gene isochorismatase domain containing 2b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    uncharacterized protein LOC684270
    Names
    isochorismatase domain-containing protein 2
    isochorismatase domain-containing protein 2A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001409142.1 → NP_001396071.1  uncharacterized protein LOC684270 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I6GL72, A6KNQ0
      Related
      ENSRNOP00000099798.1, ENSRNOT00000148451.1

    2. NM_001409143.1 → NP_001396072.1  uncharacterized protein LOC684270 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      77967751..77986002 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039100618.2 → XP_038956546.1  uncharacterized protein LOC684270 isoform X1

      UniProtKB/TrEMBL
      A0A8I6GL72, A6KNQ0
      Related
      ENSRNOP00000094488.1, ENSRNOT00000097188.2
      Conserved Domains (1) summary
      cd01012
      Location:18 → 170
      YcaC_related; YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them. ...
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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