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    Cep97 centrosomal protein 97 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 304007, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cep97provided by RGD
    Official Full Name
    centrosomal protein 97provided by RGD
    Primary source
    RGD:1307400
    See related
    EnsemblRapid:ENSRNOG00000001609 AllianceGenome:RGD:1307400
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Lrriq2; RGD1307400
    Summary
    Predicted to be involved in negative regulation of cilium assembly and regulation of mitotic spindle assembly. Predicted to be located in centriole. Predicted to be part of protein-containing complex. Predicted to be active in centrosome. Orthologous to human CEP97 (centrosomal protein 97). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 69.1), Brain (RPKM 43.1) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Cep97 in Genome Data Viewer
    Location:
    11q12
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (58152561..58187174)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (44683503..44711471)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (47146409..47174460)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 11 Neighboring gene zinc finger and BTB domain containing 11, opposite strand 1 Neighboring gene ribosomal protein L24 Neighboring gene uncharacterized LOC134481067 Neighboring gene neurexophilin and PC-esterase domain family, member 3 Neighboring gene adaptor related protein complex 3 subunit sigma 1, pseudogene 1 Neighboring gene NFKB inhibitor zeta

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in centriole  
    is_active_in centrosome  
    located_in centrosome  
    part_of protein-containing complex  

    General protein information

    Preferred Names
    centrosomal protein of 97 kDa
    Names
    centrosomal protein 97kDa
    leucine-rich repeats and IQ motif containing 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107096.1NP_001100566.1  centrosomal protein of 97 kDa

      See identical proteins and their annotated locations for NP_001100566.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473967
      UniProtKB/TrEMBL
      A6IQR0, D4AC95
      Related
      ENSRNOP00000002191.2, ENSRNOT00000002191.6
      Conserved Domains (5) summary
      cd00116
      Location:21126
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      pfam14580
      Location:107255
      LRR_9; Leucine-rich repeat
      sd00033
      Location:1737
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:103143
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:80136
      LRR_8; Leucine rich repeat

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      58152561..58187174
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039088372.2XP_038944300.1  centrosomal protein of 97 kDa isoform X3

      Conserved Domains (2) summary
      sd00033
      Location:1737
      LRR_RI; leucine-rich repeat [structural motif]
      cd21340
      Location:18242
      PPP1R42; protein phosphatase 1 regulatory subunit 42
    2. XM_039088373.2XP_038944301.1  centrosomal protein of 97 kDa isoform X4

      Conserved Domains (2) summary
      sd00033
      Location:1737
      LRR_RI; leucine-rich repeat [structural motif]
      cd21340
      Location:18242
      PPP1R42; protein phosphatase 1 regulatory subunit 42
    3. XM_063270561.1XP_063126631.1  centrosomal protein of 97 kDa isoform X1

      UniProtKB/TrEMBL
      A6IQR3
    4. XM_006248250.4XP_006248312.1  centrosomal protein of 97 kDa isoform X2

      Conserved Domains (2) summary
      pfam14580
      Location:19145
      LRR_9; Leucine-rich repeat
      sd00031
      Location:1661
      LRR_1; leucine-rich repeat [structural motif]
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