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    Nmral1 NmrA like redox sensor 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287063, updated on 9-Dec-2024

    Summary

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    Symbol
    Nmral1provided by RGD
    Full Name
    NmrA like redox sensor 1provided by RGD
    Primary source
    RGD:1311451
    See related
    EnsemblRapid:ENSRNOG00000003794 AllianceGenome:RGD:1311451
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311451
    Summary
    Predicted to enable identical protein binding activity. Predicted to be located in nucleoplasm. Orthologous to human NMRAL1 (NmrA like redox sensor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 81.4), Liver (RPKM 58.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Nmral1 in Genome Data Viewer
    Location:
    10q12
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (11348080..11356621)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (10841693..10850199)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (11045924..11055154)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene cell death-inducing p53 target 1 Neighboring gene high mobility group nucleosomal binding domain 4, pseudogene 3 Neighboring gene heme oxygenase 2 Neighboring gene DnaJ heat shock protein family (Hsp40) member A3 Neighboring gene coronin 7 Neighboring gene vasorin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Restructuring of the dinucleotide-binding fold in an NADP(H) sensor protein. Zheng X, et al. Proc Natl Acad Sci U S A, 2007 May 22. PMID 17496144, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    nmrA-like family domain-containing protein 1
    Names
    NmrA-like family domain containing 1
    nmrA-like family domain-containing protein 1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191588.1 → NP_001178517.1  nmrA-like family domain-containing protein 1

      See identical proteins and their annotated locations for NP_001178517.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A0A8I6G633, A6K4R5, D3ZDB9
      Related
      ENSRNOP00000081541.1, ENSRNOT00000114833.2
      Conserved Domains (2) summary
      cd05251
      Location:7 → 255
      NmrA_like_SDR_a; NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs
      COG0702
      Location:5 → 212
      YbjT; Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains [General function prediction only]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      11348080..11356621
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006245784.3 → XP_006245846.1  nmrA-like family domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K5K3, D3ZDB9
      Related
      ENSRNOP00000073458.1, ENSRNOT00000084850.3
      Conserved Domains (2) summary
      cd05251
      Location:7 → 249
      NmrA_like_SDR_a; NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs
      COG0702
      Location:5 → 206
      YbjT; Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains [General function prediction only]

    2. XM_039085336.2 → XP_038941264.1  nmrA-like family domain-containing protein 1 isoform X4

      Conserved Domains (1) summary
      cd05251
      Location:7 → 172
      NmrA_like_SDR_a; NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs

    3. XM_063268526.1 → XP_063124596.1  nmrA-like family domain-containing protein 1 isoform X3

    4. XM_039085335.2 → XP_038941263.1  nmrA-like family domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      D3ZDB9
      Conserved Domains (1) summary
      cl21454
      Location:1 → 176
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P86172.1 GenPept UniProtKB/Swiss-Prot:P86172

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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