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    Fam50b family with sequence similarity 50, member B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 306883, updated on 9-Dec-2024

    Summary

    Official Symbol
    Fam50bprovided by RGD
    Official Full Name
    family with sequence similarity 50, member Bprovided by RGD
    Primary source
    RGD:1563458
    See related
    EnsemblRapid:ENSRNOG00000017083 AllianceGenome:RGD:1563458
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563458
    Summary
    Predicted to be involved in chromatin organization. Predicted to be located in intercellular bridge; midbody; and nucleoplasm. Predicted to be active in nucleus. Orthologous to human FAM50B (family with sequence similarity 50 member B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 116.9) See more
    Orthologs
    NEW
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    Genomic context

    See Fam50b in Genome Data Viewer
    Location:
    17p12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (30379796..30399399, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (30174431..30193627, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (30864189..30883427, complement)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene pre-mRNA processing factor 4B Neighboring gene high mobility group box 1, pseudogene 2 Neighboring gene PX domain containing 1 Neighboring gene solute carrier family 22, member 23 Neighboring gene uncharacterized LOC134482704

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in chromatin organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in intercellular bridge IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intercellular bridge ISO
    Inferred from Sequence Orthology
    more info
     
    located_in midbody IEA
    Inferred from Electronic Annotation
    more info
     
    located_in midbody ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107349.1NP_001100819.1  protein FAM50B

      See identical proteins and their annotated locations for NP_001100819.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473977
      UniProtKB/TrEMBL
      A6J7F4, D3Z9C2
      Conserved Domains (1) summary
      pfam04921
      Location:136334
      XAP5; XAP5, circadian clock regulator

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      30379796..30399399 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006253827.5XP_006253889.1  protein FAM50B isoform X1

      See identical proteins and their annotated locations for XP_006253889.1

      UniProtKB/TrEMBL
      A6J7F4, D3Z9C2
      Related
      ENSRNOP00000022929.2, ENSRNOT00000022929.5
      Conserved Domains (1) summary
      pfam04921
      Location:136334
      XAP5; XAP5, circadian clock regulator