U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Exoc3 exocyst complex component 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 252881, updated on 9-Dec-2024

    Summary

    Official Symbol
    Exoc3provided by RGD
    Official Full Name
    exocyst complex component 3provided by RGD
    Primary source
    RGD:621790
    See related
    AllianceGenome:RGD:621790
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Sec6; rSec6; Sec6l1
    Summary
    Predicted to enable SNARE binding activity. Predicted to be involved in exocyst localization and exocytosis. Is active in presynaptic membrane. Orthologous to human EXOC3 (exocyst complex component 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 164.4), Brain (RPKM 161.5) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Exoc3 in Genome Data Viewer
    Location:
    1p11
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (30919871..30950624)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (29091298..29122056)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (31700953..31731726)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene aryl-hydrocarbon receptor repressor Neighboring gene dynein axonemal assembly factor 8-like Neighboring gene uncharacterized LOC108349507 Neighboring gene solute carrier family 9 member A3 Neighboring gene centrosomal protein 72

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables SNARE binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in exocyst localization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in exocytosis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of exocyst IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of exocyst IEA
    Inferred from Electronic Annotation
    more info
     
    located_in growth cone IEA
    Inferred from Electronic Annotation
    more info
     
    located_in midbody IEA
    Inferred from Electronic Annotation
    more info
     
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in presynaptic membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    exocyst complex component 3
    Names
    SEC6-like 1
    exocyst complex component Sec6

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024964.1NP_001020135.1  exocyst complex component 3

      See identical proteins and their annotated locations for NP_001020135.1

      Status: PROVISIONAL

      Source sequence(s)
      BC097993
      UniProtKB/Swiss-Prot
      Q4QQU2, Q62825
      UniProtKB/TrEMBL
      A0A8L2QA79, A6JUV0
      Conserved Domains (1) summary
      pfam06046
      Location:187743
      Sec6; Exocyst complex component Sec6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      30919871..30950624
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006227767.5XP_006227829.1  exocyst complex component 3 isoform X1

      See identical proteins and their annotated locations for XP_006227829.1

      UniProtKB/Swiss-Prot
      Q4QQU2, Q62825
      UniProtKB/TrEMBL
      A0A8L2QA79, A6JUV0
      Conserved Domains (1) summary
      pfam06046
      Location:187743
      Sec6; Exocyst complex component Sec6
    2. XM_006227768.5XP_006227830.1  exocyst complex component 3 isoform X1

      See identical proteins and their annotated locations for XP_006227830.1

      UniProtKB/Swiss-Prot
      Q4QQU2, Q62825
      UniProtKB/TrEMBL
      A0A8L2QA79, A6JUV0
      Conserved Domains (1) summary
      pfam06046
      Location:187743
      Sec6; Exocyst complex component Sec6