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    Fam227a family with sequence similarity 227, member A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 300074, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fam227aprovided by RGD
    Official Full Name
    family with sequence similarity 227, member Aprovided by RGD
    Primary source
    RGD:1305939
    See related
    EnsemblRapid:ENSRNOG00000021795 AllianceGenome:RGD:1305939
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305939
    Summary
    Orthologous to human FAM227A (family with sequence similarity 227 member A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 46.6), Testes (RPKM 36.4) and 4 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Fam227a in Genome Data Viewer
    Location:
    7q34
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (113054751..113096898, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (111174362..111216513, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (120846166..120891738, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene DEAD-box helicase 17 Neighboring gene DNA meiotic recombinase 1 Neighboring gene uncharacterized LOC134479938 Neighboring gene chibby 1, beta catenin antagonist Neighboring gene translocase of outer mitochondrial membrane 22

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    protein FAM227A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001130581.3 → NP_001124053.2  protein FAM227A

      See identical proteins and their annotated locations for NP_001124053.2

      Status: VALIDATED

      Source sequence(s)
      BC097470, JAXUCZ010000007
      UniProtKB/TrEMBL
      F1LMV2
      Related
      ENSRNOP00000053025.5, ENSRNOT00000056179.7
      Conserved Domains (1) summary
      pfam14922
      Location:136 → 297
      FWWh; Protein of unknown function

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      113054751..113096898 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039078836.1 → XP_038934764.1  protein FAM227A isoform X1

      Conserved Domains (1) summary
      pfam14922
      Location:147 → 297
      FWWh; Protein of unknown function

    2. XM_039078837.1 → XP_038934765.1  protein FAM227A isoform X2

      UniProtKB/TrEMBL
      A0A0G2JTT0, Q4V8A5
      Related
      ENSRNOP00000068832.2, ENSRNOT00000078320.3
      Conserved Domains (1) summary
      pfam14922
      Location:147 → 297
      FWWh; Protein of unknown function

    RNA

    1. XR_005486589.2 RNA Sequence

    2. XR_010052960.1 RNA Sequence

    3. XR_005486591.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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