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    Polr2k RNA polymerase II, I and III subunit K [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100361574, updated on 9-Dec-2024

    Summary

    Official Symbol
    Polr2kprovided by RGD
    Official Full Name
    RNA polymerase II, I and III subunit Kprovided by RGD
    Primary source
    RGD:2319895
    See related
    EnsemblRapid:ENSRNOG00000072843 AllianceGenome:RGD:2319895
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to contribute to RNA polymerase I activity; RNA polymerase II activity; and RNA polymerase III activity. Predicted to be involved in transcription by RNA polymerase I and transcription by RNA polymerase III. Predicted to act upstream of or within transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of RNA polymerase I complex; RNA polymerase II, core complex; and RNA polymerase III complex. Orthologous to human POLR2K (RNA polymerase II, I and III subunit K). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 340.2), Adrenal (RPKM 317.8) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Polr2k in Genome Data Viewer
    Location:
    7q22
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (69241233..69244579)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (67347118..67359466)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (74939010..74992594)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479892 Neighboring gene F-box protein 43 Neighboring gene sperm associated antigen 1 Neighboring gene U4 spliceosomal RNA Neighboring gene ring finger protein 19A, RBR E3 ubiquitin protein ligase Neighboring gene ring finger protein 19A, RBR E3 ubiquitin protein ligase like 1

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to RNA polymerase I activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    contributes_to RNA polymerase II activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    contributes_to RNA polymerase III activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in transcription by RNA polymerase I IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in transcription by RNA polymerase III IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of RNA polymerase I complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of RNA polymerase I complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of RNA polymerase II, core complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of RNA polymerase II, core complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of RNA polymerase III complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of RNA polymerase III complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    DNA-directed RNA polymerases I, II, and III subunit RPABC4
    Names
    RNA polymerase II subunit K
    mCG145114-like
    polymerase (RNA) II (DNA directed) polypeptide K
    NP_001269254.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001282325.1NP_001269254.1  DNA-directed RNA polymerases I, II, and III subunit RPABC4

      See identical proteins and their annotated locations for NP_001269254.1

      Status: VALIDATED

      Source sequence(s)
      AW144706, EX488432
      UniProtKB/TrEMBL
      A6HR24
      Related
      ENSRNOP00000108896.1, ENSRNOT00000131056.1
      Conserved Domains (1) summary
      smart00659
      Location:1558
      RPOLCX; RNA polymerase subunit CX

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      69241233..69244579
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)