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    Mterf2 mitochondrial transcription termination factor 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 366856, updated on 9-Dec-2024

    Summary

    Official Symbol
    Mterf2provided by RGD
    Official Full Name
    mitochondrial transcription termination factor 2provided by RGD
    Primary source
    RGD:1311836
    See related
    EnsemblRapid:ENSRNOG00000006978 AllianceGenome:RGD:1311836
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Mterfd3; RGD1311836
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in termination of mitochondrial transcription. Predicted to be located in mitochondrial nucleoid. Predicted to be active in mitochondrial matrix. Orthologous to human MTERF2 (mitochondrial transcription termination factor 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 78.9), Muscle (RPKM 67.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Mterf2 in Genome Data Viewer
    Location:
    7q13
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (20485901..20495979)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (18598202..18608278)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (24638208..24649599)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479646 Neighboring gene sialic acid synthase-like Neighboring gene cryptochrome circadian regulator 1 Neighboring gene transmembrane protein 263 Neighboring gene four and a half LIM domains 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC112659

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables double-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleic acid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in termination of mitochondrial transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrial nucleoid IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial nucleoid ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial nucleoid ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    transcription termination factor 2, mitochondrial
    Names
    MTERF domain containing 3
    mTERF domain-containing protein 3, mitochondrial

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014265.2NP_001014287.1  transcription termination factor 2, mitochondrial precursor

      See identical proteins and their annotated locations for NP_001014287.1

      Status: VALIDATED

      Source sequence(s)
      BC098693
      UniProtKB/Swiss-Prot
      Q5XIE2
      Related
      ENSRNOP00000009135.4, ENSRNOT00000009135.6
      Conserved Domains (1) summary
      cl19765
      Location:84360
      mTERF; mTERF

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      20485901..20495979
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039079676.1XP_038935604.1  transcription termination factor 2, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8I6GHQ6, A6IFE3
      Related
      ENSRNOP00000105730.1, ENSRNOT00000132892.1
      Conserved Domains (1) summary
      cl19765
      Location:93369
      mTERF
    2. XM_063264025.1XP_063120095.1  transcription termination factor 2, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8I6GHQ6, A6IFE3
      Related
      ENSRNOP00000110681.1, ENSRNOT00000141015.1