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    Harbi1 harbinger transposase derived 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 690164, updated on 9-Dec-2024

    Summary

    Official Symbol
    Harbi1provided by RGD
    Official Full Name
    harbinger transposase derived 1provided by RGD
    Primary source
    RGD:1584007
    See related
    EnsemblRapid:ENSRNOG00000081861 AllianceGenome:RGD:1584007
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable metal ion binding activity and nuclease activity. Predicted to be located in centriolar satellite; cytosol; and plasma membrane. Orthologous to human HARBI1 (harbinger transposase derived 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 21.5), Kidney (RPKM 19.6) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Harbi1 in Genome Data Viewer
    Location:
    3q24
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (98137087..98145992)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (77681431..77689749)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (80614886..80624213)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 408 Neighboring gene Rho GTPase activating protein 1 Neighboring gene autophagy related 13 Neighboring gene autophagy and beclin 1 regulator 1 Neighboring gene uncharacterized LOC134486121 Neighboring gene cholinergic receptor, muscarinic 4 Neighboring gene midkine

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    putative nuclease HARBI1
    Names
    Harbinger transposase-derived nuclease
    NP_001107265.2
    XP_063140650.1
    XP_063140651.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001113793.3NP_001107265.2  putative nuclease HARBI1

      See identical proteins and their annotated locations for NP_001107265.2

      Status: VALIDATED

      Source sequence(s)
      BC158734
      UniProtKB/Swiss-Prot
      B0BN95
      Conserved Domains (1) summary
      pfam13359
      Location:148300
      DDE_Tnp_4; DDE superfamily endonuclease

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      98137087..98145992
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063284581.1XP_063140651.1  putative nuclease HARBI1 isoform X1

      Related
      ENSRNOP00000108066.1, ENSRNOT00000132207.1
    2. XM_063284580.1XP_063140650.1  putative nuclease HARBI1 isoform X1