Chst12 carbohydrate sulfotransferase 12 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Chst12provided by RGD
Official Full Name: carbohydrate sulfotransferase 12provided by RGD
Primary source: RGD:1308214
See related: EnsemblRapid:ENSRNOG00000001252 AllianceGenome:RGD:1308214
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and dermatan sulfate biosynthetic process. Predicted to be located in Golgi membrane. Biomarker of hypertension. Orthologous to human CHST12 (carbohydrate sulfotransferase 12). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Spleen (RPKM 32.2), Lung (RPKM 23.5) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 12q11

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	12	NC_086030.1 (19224545..19243012, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	12	NC_051347.1 (14110631..14129099, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	12	NC_005111.4 (16199975..16218404, complement)

Chromosome 12 - NC_086030.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

UniSTS:235351 (e-PCR)
- UniSTS:235351

AI595374 (e-PCR)
- UniSTS:179304

RH143860 (e-PCR)
- UniSTS:233106

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables chondroitin 4-sulfotransferase activity	ISO Inferred from Sequence Orthology more info
enables sulfotransferase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in carbohydrate biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in chondroitin sulfate biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in dermatan sulfate biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in proteoglycan biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: carbohydrate sulfotransferase 12

Names: carbohydrate (chondroitin 4) sulfotransferase 12

NP_001032864.1

EC 2.8.2.5

XP_006248997.1

EC 2.8.2.5

XP_006248999.1

EC 2.8.2.5

XP_017453811.1

EC 2.8.2.5

XP_038945315.1

EC 2.8.2.5

XP_063127342.1

EC 2.8.2.5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.