Asxl3 ASXL transcriptional regulator 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Asxl3provided by RGD
Official Full Name: ASXL transcriptional regulator 3provided by RGD
Primary source: RGD:1305869
See related: EnsemblRapid:ENSRNOG00000015383 AllianceGenome:RGD:1305869
Gene type: protein coding
RefSeq status: MODEL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1305869
Summary: Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be involved in negative regulation of lipid biosynthetic process. Human ortholog(s) of this gene implicated in Bainbridge-Ropers syndrome. Orthologous to human ASXL3 (ASXL transcriptional regulator 3). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 15.6), Spleen (RPKM 3.6) and 7 other tissues See more
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	18	NC_086036.1 (13868223..14040867)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	18	NC_051353.1 (13593529..13766324)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	18	NC_005117.4 (13322148..13496230)

Chromosome 18 - NC_086036.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables chromatin binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables peroxisome proliferator activated receptor binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in animal organ morphogenesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of lipid biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info