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    Tmem270 transmembrane protein 270 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288604, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tmem270provided by RGD
    Official Full Name
    transmembrane protein 270provided by RGD
    Primary source
    RGD:1561903
    See related
    EnsemblRapid:ENSRNOG00000001474 AllianceGenome:RGD:1561903
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Wbscr28; RGD1561903
    Summary
    Predicted to be located in membrane. Orthologous to human TMEM270 (transmembrane protein 270). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 106.1) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tmem270 in Genome Data Viewer
    Location:
    12q12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (27430092..27435243)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (21793631..21798723)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (24803204..24808287)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene claudin-4-like Neighboring gene methyltransferase like 27 Neighboring gene uncharacterized LOC120095920 Neighboring gene uncharacterized LOC102553484 Neighboring gene elastin Neighboring gene LIM domain kinase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 270
    Names
    Williams-Beuren syndrome chromosome region 28

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001431982.1 → NP_001418911.1  transmembrane protein 270 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      D3ZKV0

    2. NM_001431983.1 → NP_001418912.1  transmembrane protein 270 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A0A8I6G8Y8

    3. NM_001431984.1 → NP_001418913.1  transmembrane protein 270 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012

    4. NM_001431985.1 → NP_001418914.1  transmembrane protein 270 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      27430092..27435243
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006249213.5 → XP_006249275.1  transmembrane protein 270 isoform X1

      Related
      ENSRNOP00000106875.1, ENSRNOT00000165625.1
      Conserved Domains (1) summary
      pfam15164
      Location:61 → 300
      WBS28; Williams-Beuren syndrome chromosomal region 28 protein homologue

    2. XM_213758.11 → XP_213758.4  transmembrane protein 270 isoform X3

      Related
      ENSRNOP00000034323.3, ENSRNOT00000033499.7
      Conserved Domains (1) summary
      pfam15164
      Location:1 → 264
      WBS28; Williams-Beuren syndrome chromosomal region 28 protein homologue

    3. XM_017598507.2 → XP_017453996.1  transmembrane protein 270 isoform X2

      Related
      ENSRNOP00000082087.1, ENSRNOT00000114794.2
    Nucleotide Protein Strain
    Heading Accession and Version

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