Gtpbp6 GTP binding protein 6 (putative) [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Gtpbp6provided by RGD
Full Name: GTP binding protein 6 (putative)provided by RGD
Primary source: RGD:1305954
See related: EnsemblRapid:ENSRNOG00000062521 AllianceGenome:RGD:1305954
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1305954
Summary: Predicted to enable ribosome binding activity. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Orthologous to human GTPBP6 (GTP binding protein 6 (putative)). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Adrenal (RPKM 81.1), Muscle (RPKM 80.9) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 12q16

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	12	NC_086030.1 (52234646..52238578)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	12	NC_051347.1 (46574913..46578873)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	12	NC_005111.4 (52637000..52640869)

Chromosome 12 - NC_086030.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables ribosome binding	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info	PubMed

General protein information

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Preferred Names: putative GTP-binding protein 6

Names: putative GTP-binding protein 6-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001135840.1 → NP_001129312.1 putative GTP-binding protein 6

Status: PROVISIONAL

Source sequence(s)

JAXUCZ010000012

UniProtKB/TrEMBL

A0A8I5ZU18

Related

ENSRNOP00000080925.1, ENSRNOT00000105776.2

Conserved Domains (4) summary

cd01878
Location:270 → 441

HflX; HflX GTPase family

COG2262
Location:105 → 501

HflX; 50S ribosomal subunit-associated GTPase HflX [Translation, ribosomal structure and biogenesis]

pfam13167
Location:109 → 195

GTP-bdg_N; GTP-binding GTPase N-terminal

pfam16360
Location:199 → 255

GTP-bdg_M; GTP-binding GTPase Middle Region