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    Cops9 COP9 signalosome subunit 9 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 681389, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cops9provided by RGD
    Official Full Name
    COP9 signalosome subunit 9provided by RGD
    Primary source
    RGD:1596701
    See related
    EnsemblRapid:ENSRNOG00000037402 AllianceGenome:RGD:1596701
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Myeov2
    Summary
    Predicted to be involved in several processes, including cellular response to UV; cytoplasmic sequestering of protein; and negative regulation of protein neddylation. Predicted to be located in chromatin; cytoplasm; and nucleoplasm. Predicted to be part of COP9 signalosome. Orthologous to human COPS9 (COP9 signalosome subunit 9). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 642.6), Heart (RPKM 614.0) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cops9 in Genome Data Viewer
    Location:
    9q36
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (100657276..100662206, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (93209843..93214774, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (99813332..99818262, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 9 subfamily S member 14 Neighboring gene olfactory receptor family 9 subfamily S member 13 Neighboring gene uncharacterized LOC134480610 Neighboring gene otospiralin Neighboring gene uncharacterized LOC134480418

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cellular response to UV ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cytoplasmic sequestering of protein ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of protein neddylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of COP9 signalosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    COP9 signalosome complex subunit 9
    Names
    myeloma overexpressed 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109044.1NP_001102514.1  COP9 signalosome complex subunit 9

      See identical proteins and their annotated locations for NP_001102514.1

      Status: VALIDATED

      Source sequence(s)
      CR465509, DV717666
      UniProtKB/TrEMBL
      B5DFN0
      Related
      ENSRNOP00000104739.1, ENSRNOT00000135389.1
      Conserved Domains (1) summary
      pfam15004
      Location:150
      MYEOV2; Myeloma-overexpressed-like

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      100657276..100662206 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)