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    Mxd3 Max dimerization protein 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 252915, updated on 9-Dec-2024

    Summary

    Official Symbol
    Mxd3provided by RGD
    Official Full Name
    Max dimerization protein 3provided by RGD
    Primary source
    RGD:628624
    See related
    EnsemblRapid:ENSRNOG00000070523 AllianceGenome:RGD:628624
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Myx; Mad3
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to contribute to DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of DNA-templated transcription. Predicted to be part of RNA polymerase II transcription regulator complex. Orthologous to human MXD3 (MAX dimerization protein 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 76.2), Spleen (RPKM 28.2) and 7 other tissues See more
    Orthologs
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    Genomic context

    See Mxd3 in Genome Data Viewer
    Location:
    17p14
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (9306552..9310278)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (9301430..9305156)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (9830326..9834052)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene lectin, mannose-binding 2 Neighboring gene uncharacterized LOC134482676 Neighboring gene PRELI domain containing 1 Neighboring gene RAB24, member RAS oncogene family

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    part_of RNA polymerase II transcription regulator complex  
    part_of RNA polymerase II transcription regulator complex  

    General protein information

    Preferred Names
    max dimerization protein 3
    Names
    max dimerizer 3
    max-associated protein 3
    max-interacting transcriptional repressor MAD3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145773.2NP_665716.2  max dimerization protein 3

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/Swiss-Prot
      Q62912
      UniProtKB/TrEMBL
      A6KAU0, G3V831
      Related
      ENSRNOP00000094537.1, ENSRNOT00000104750.2
      Conserved Domains (1) summary
      cl00081
      Location:53122
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      9306552..9310278
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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