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    Serpine3 serpin family E member 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 691375, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Serpine3provided by RGD
    Official Full Name
    serpin family E member 3provided by RGD
    Primary source
    RGD:1585042
    See related
    EnsemblRapid:ENSRNOG00000009814 AllianceGenome:RGD:1585042
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310515
    Summary
    Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to be active in extracellular space. Orthologous to human SERPINE3 (serpin family E member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 38.2), Thymus (RPKM 37.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Serpine3 in Genome Data Viewer
    Location:
    15p12
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (41084819..41109006)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (36908816..36931825)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (45827983..45855952)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 124 member A Neighboring gene uncharacterized LOC134482129 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene ribosomal protein L38, pseudogene 7 Neighboring gene integrator complex subunit 6 Neighboring gene Sec61 translocon subunit gamma, pseudogene 5 Neighboring gene zinc finger CCCH domain-containing protein 13-like Neighboring gene large ribosomal subunit protein eL27-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    serpin E3
    Names
    serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      41084819..41109006
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063274875.1 → XP_063130945.1  serpin E3

      UniProtKB/TrEMBL
      D4A9F7
      Related
      ENSRNOP00000045922.3, ENSRNOT00000051307.6
    Nucleotide Protein Strain
    Heading Accession and Version

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