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    Tmem150c transmembrane protein 150C [ Rattus norvegicus (Norway rat) ]

    Gene ID: 360916, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tmem150cprovided by RGD
    Official Full Name
    transmembrane protein 150Cprovided by RGD
    Primary source
    RGD:1306105
    See related
    EnsemblRapid:ENSRNOG00000002258 AllianceGenome:RGD:1306105
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306105
    Summary
    Predicted to enable mechanosensitive monoatomic cation channel activity. Predicted to be involved in cellular response to mechanical stimulus and proprioception. Predicted to be located in lysosomal membrane. Predicted to be active in plasma membrane. Orthologous to human TMEM150C (transmembrane protein 150C). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 75.9), Brain (RPKM 57.3) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tmem150c in Genome Data Viewer
    Location:
    14p22
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (9759028..9829588)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (9454999..9525300)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (11094655..11166323)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134481704 Neighboring gene uncharacterized LOC134481707 Neighboring gene uncharacterized LOC134481706 Neighboring gene enolase-phosphatase 1 Neighboring gene uncharacterized LOC134481708 Neighboring gene heterogeneous nuclear ribonucleoprotein D-like

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables mechanosensitive monoatomic cation channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables mechanosensitive monoatomic cation channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in cellular response to mechanical stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to mechanical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in monoatomic cation transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in proprioception ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in proprioception ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in lysosomal membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108354.3NP_001101824.1  transmembrane protein 150C

      See identical proteins and their annotated locations for NP_001101824.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000014
      UniProtKB/Swiss-Prot
      B5DFH9
      Related
      ENSRNOP00000110270.1, ENSRNOT00000138364.1
      Conserved Domains (1) summary
      pfam10277
      Location:8217
      Frag1; Frag1/DRAM/Sfk1 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      9759028..9829588
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006250670.5XP_006250732.1  transmembrane protein 150C isoform X1

      See identical proteins and their annotated locations for XP_006250732.1

      UniProtKB/Swiss-Prot
      B5DFH9
      Conserved Domains (1) summary
      pfam10277
      Location:8217
      Frag1; Frag1/DRAM/Sfk1 family
    2. XM_063273331.1XP_063129401.1  transmembrane protein 150C isoform X1

      UniProtKB/Swiss-Prot
      B5DFH9
    3. XM_063273332.1XP_063129402.1  transmembrane protein 150C isoform X2