Fbxl14 F-box and leucine-rich repeat protein 14 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Fbxl14provided by RGD
Official Full Name: F-box and leucine-rich repeat protein 14provided by RGD
Primary source: RGD:1305523
See related: EnsemblRapid:ENSRNOG00000070828 AllianceGenome:RGD:1305523
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be active in cytoplasm. Orthologous to human FBXL14 (F-box and leucine rich repeat protein 14). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: 4q42

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (154334820..154338638)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (152662542..152666360)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (151986890..151990706)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ubiquitin-protein transferase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in ubiquitin-dependent protein catabolic process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: F-box/LRR-repeat protein 14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001271276.2 → NP_001258205.1 F-box/LRR-repeat protein 14

See identical proteins and their annotated locations for NP_001258205.1

Status: PROVISIONAL

Source sequence(s)

JAXUCZ010000004

UniProtKB/TrEMBL

A0A8I6GI29, A6IL86

Related

ENSRNOP00000089410.1, ENSRNOT00000094505.2

Conserved Domains (3) summary

cd09293
Location:228 → 395

AMN1; Antagonist of mitotic exit network protein 1

sd00034
Location:145 → 170

LRR_AMN1; leucine-rich repeat [structural motif]

pfam12937
Location:5 → 46

F-box-like