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    Gdpd2 glycerophosphodiester phosphodiesterase domain containing 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 302421, updated on 9-Dec-2024

    Summary

    Official Symbol
    Gdpd2provided by RGD
    Official Full Name
    glycerophosphodiester phosphodiesterase domain containing 2provided by RGD
    Primary source
    RGD:1560780
    See related
    EnsemblRapid:ENSRNOG00000002800 AllianceGenome:RGD:1560780
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1560780
    Summary
    Predicted to enable glycerophosphodiester phosphodiesterase activity. Predicted to be involved in lipid metabolic process. Predicted to act upstream of or within actin filament organization and positive regulation of osteoblast differentiation. Predicted to be located in actin filament and lamellipodium. Predicted to be active in plasma membrane. Orthologous to human GDPD2 (glycerophosphodiester phosphodiesterase domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 175.3), Brain (RPKM 17.9) and 1 other tissue See more
    Orthologs
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    Genomic context

    See Gdpd2 in Genome Data Viewer
    Location:
    Xq22
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (69866395..69875419)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (65826273..65835361)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (70563381..70572295)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120099344 Neighboring gene kinesin family member 4A Neighboring gene transfer RNA phenylalanine (anticodon GAA) 8 Neighboring gene discs large MAGUK scaffold protein 3 Neighboring gene testis expressed 11 Neighboring gene sarcoglycan, beta, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in actin filament  
    located_in lamellipodium  
    is_active_in plasma membrane  
    located_in plasma membrane  

    General protein information

    Preferred Names
    glycerophosphoinositol inositolphosphodiesterase GDPD2
    NP_001100414.1
    XP_006257126.1
    XP_038955521.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106944.1 → NP_001100414.1  glycerophosphoinositol inositolphosphodiesterase GDPD2

      See identical proteins and their annotated locations for NP_001100414.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473966
      UniProtKB/TrEMBL
      A6IQ87, D3Z9K9
      Related
      ENSRNOP00000003772.3, ENSRNOT00000003772.7
      Conserved Domains (1) summary
      cl14615
      Location:198 → 499
      PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      69866395..69875419
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039099593.2 → XP_038955521.1  glycerophosphoinositol inositolphosphodiesterase GDPD2 isoform X1

      UniProtKB/TrEMBL
      A6IQ87, D3Z9K9
      Conserved Domains (1) summary
      cl14615
      Location:198 → 499
      PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
    2. XM_006257064.5 → XP_006257126.1  glycerophosphoinositol inositolphosphodiesterase GDPD2 isoform X1

      See identical proteins and their annotated locations for XP_006257126.1

      UniProtKB/TrEMBL
      A6IQ87, D3Z9K9
      Conserved Domains (1) summary
      cl14615
      Location:198 → 499
      PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
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