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    C1h10orf88 similar to human chromosome 10 open reading frame 88 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 309029, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C1h10orf88provided by RGD
    Official Full Name
    similar to human chromosome 10 open reading frame 88provided by RGD
    Primary source
    RGD:1305014
    See related
    EnsemblRapid:ENSRNOG00000020597 AllianceGenome:RGD:1305014
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    PAAT; RGD1305014
    Summary
    Predicted to enable ATP hydrolysis activity and identical protein binding activity. Predicted to be located in mitochondrion. Orthologous to several human genes including C10orf88 (chromosome 10 open reading frame 88). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 31.0), Thymus (RPKM 29.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See C1h10orf88 in Genome Data Viewer
    Location:
    1q41
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (195555517..195580177, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (186132360..186149932, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (201924779..201943014, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 24 member B Neighboring gene family with sequence similarity 24, member A Neighboring gene phosphoseryl-tRNA kinase Neighboring gene IKAROS family zinc finger 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. PAAT, a novel ATPase and trans-regulator of mitochondrial ABC transporters, is critically involved in the maintenance of mitochondrial homeostasis. Yang X, et al. FASEB J, 2014 Nov. PMID 25063848
    2. Protein-protein interaction panel using mouse full-length cDNAs. Suzuki H, et al. Genome Res, 2001 Oct. PMID 11591653, Free PMC Article
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables ATP hydrolysis activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables ATP-dependent H2AZ histone chaperone activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP-dependent H3-H4 histone complex chaperone activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA clamp loader activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables chromatin extrusion motor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cohesin loader activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin looping IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    ATPase PAAT
    Names
    protein associated with ABC transporters
    uncharacterized protein C10orf88 homolog
    NP_001014047.1
    XP_008758107.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014025.1 → NP_001014047.1  ATPase PAAT

      See identical proteins and their annotated locations for NP_001014047.1

      Status: PROVISIONAL

      Source sequence(s)
      BC083846
      UniProtKB/Swiss-Prot
      Q5XI46
      UniProtKB/TrEMBL
      A6HWV8
      Related
      ENSRNOP00000027956.4, ENSRNOT00000027956.8
      Conserved Domains (1) summary
      pfam14958
      Location:59 → 197
      DUF4506; Domain of unknown function (DUF4506)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      195555517..195580177 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008759885.4 → XP_008758107.1  ATPase PAAT isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZT74
      Related
      ENSRNOP00000081975.1, ENSRNOT00000096199.2
      Conserved Domains (1) summary
      pfam14958
      Location:59 → 197
      DUF4506; Domain of unknown function (DUF4506)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XI46.1 GenPept UniProtKB/Swiss-Prot:Q5XI46

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
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