U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    UBBP4 ubiquitin B pseudogene 4 [ Homo sapiens (human) ]

    Gene ID: 23666, updated on 10-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    UBBP4provided by HGNC
    Official Full Name
    ubiquitin B pseudogene 4provided by HGNC
    Primary source
    HGNC:HGNC:12467
    See related
    Ensembl:ENSG00000290919 AllianceGenome:HGNC:12467
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See UBBP4 in Genome Data Viewer
    Location:
    17p11.2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (22090750..22205151)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (22756789..22866794)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (20771840..21731757)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:21561832-21562394 Neighboring gene abhydrolase domain containing 15 pseudogene Neighboring gene MPRA-validated peak2767 silencer Neighboring gene ReSE screen-validated silencer GRCh37_chr17:21532008-21532206 Neighboring gene NCOR1 pseudogene 2 Neighboring gene ferritin light chain pseudogene 13 Neighboring gene long intergenic non-protein coding RNA 2002

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. UBB pseudogene 4 encodes functional ubiquitin variants. Dubois ML, et al. Nat Commun, 2020 Mar 11. PMID 32161257, Free PMC Article
    2. Human ubiquitin genes: one member of the UbB gene subfamily is a tetrameric non-processed pseudogene. Cowland JB, et al. FEBS Lett, 1988 Apr 11. PMID 2834222
    3. Localization of the human UbB polyubiquitin gene to chromosome band 17p11.1-17p12. Webb GC, et al. Am J Hum Genet, 1990 Feb. PMID 2154095, Free PMC Article
    4. PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805. Bai Y, et al. Autophagy, 2023 May. PMID 36300783, Free PMC Article
    5. Proteomic analysis of the cullin 4B interactome using proximity-dependent biotinylation in living cells. Zhang H, et al. Proteomics, 2017 Apr. PMID 28225217

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

    Go to the top of the page Help

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

    Go to the top of the page Help

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_144546.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC138761
      Related
      ENST00000584755.3

    2. NR_176224.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      ABBA01006765, AC138761
      Related
      ENST00000648259.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

      Range
      22090750..22205151
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060941.1 Alternate T2T-CHM13v2.0

      Range
      22756789..22866794
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials