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    Fbxo46 F-box protein 46 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292686, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fbxo46provided by RGD
    Official Full Name
    F-box protein 46provided by RGD
    Primary source
    RGD:1308393
    See related
    EnsemblRapid:ENSRNOG00000008815 AllianceGenome:RGD:1308393
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Orthologous to human FBXO46 (F-box protein 46). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 45.7), Testes (RPKM 44.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Fbxo46 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (87898029..87914615)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (78770059..78786582)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (80028873..80045666)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene DM1 protein kinase Neighboring gene SIX homeobox 5 Neighboring gene meiosis initiator Neighboring gene glutaminyl-peptide cyclotransferase-like Neighboring gene small nuclear ribonucleoprotein D2 polypeptide

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC114545

    General protein information

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    Preferred Names
    F-box only protein 46

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025642.1 → NP_001020813.1  F-box only protein 46

      See identical proteins and their annotated locations for NP_001020813.1

      Status: PROVISIONAL

      Source sequence(s)
      BC098945
      UniProtKB/Swiss-Prot
      Q4KLY2
      UniProtKB/TrEMBL
      A6J8J9
      Related
      ENSRNOP00000104882.1, ENSRNOT00000122695.1
      Conserved Domains (1) summary
      pfam12937
      Location:473 → 507
      F-box-like

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      87898029..87914615
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006228399.5 → XP_006228461.1  F-box only protein 46 isoform X1

      See identical proteins and their annotated locations for XP_006228461.1

      UniProtKB/Swiss-Prot
      Q4KLY2
      UniProtKB/TrEMBL
      A6J8J9
      Related
      ENSRNOP00000103398.1, ENSRNOT00000139630.1
      Conserved Domains (1) summary
      pfam12937
      Location:473 → 507
      F-box-like

    2. XM_039103955.2 → XP_038959883.1  F-box only protein 46 isoform X1

      UniProtKB/Swiss-Prot
      Q4KLY2
      UniProtKB/TrEMBL
      A6J8J9
      Related
      ENSRNOP00000104645.1, ENSRNOT00000155506.1
      Conserved Domains (1) summary
      pfam12937
      Location:473 → 507
      F-box-like

    3. XM_039103964.2 → XP_038959892.1  F-box only protein 46 isoform X1

      UniProtKB/Swiss-Prot
      Q4KLY2
      UniProtKB/TrEMBL
      A6J8J9
      Related
      ENSRNOP00000112051.1, ENSRNOT00000171860.1
      Conserved Domains (1) summary
      pfam12937
      Location:473 → 507
      F-box-like

    4. XM_006228400.5 → XP_006228462.1  F-box only protein 46 isoform X1

      See identical proteins and their annotated locations for XP_006228462.1

      UniProtKB/Swiss-Prot
      Q4KLY2
      UniProtKB/TrEMBL
      A6J8J9
      Related
      ENSRNOP00000099991.1, ENSRNOT00000162291.1
      Conserved Domains (1) summary
      pfam12937
      Location:473 → 507
      F-box-like

    5. XM_006228401.5 → XP_006228463.1  F-box only protein 46 isoform X1

      See identical proteins and their annotated locations for XP_006228463.1

      UniProtKB/Swiss-Prot
      Q4KLY2
      UniProtKB/TrEMBL
      A6J8J9
      Related
      ENSRNOP00000097011.1, ENSRNOT00000119270.2
      Conserved Domains (1) summary
      pfam12937
      Location:473 → 507
      F-box-like
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4KLY2.1 GenPept UniProtKB/Swiss-Prot:Q4KLY2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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