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    Zfp672 zinc finger protein 672 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 303165, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp672provided by RGD
    Official Full Name
    zinc finger protein 672provided by RGD
    Primary source
    RGD:1359094
    See related
    EnsemblRapid:ENSRNOG00000002713 AllianceGenome:RGD:1359094
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Znf672
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to human ZNF672 (zinc finger protein 672). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 53.8), Kidney (RPKM 50.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp672 in Genome Data Viewer
    Location:
    10q22
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (42996996..43012564, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (42496558..42512134, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (43752699..43768291, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene transfer RNA glutamic acid (anticodon CUC) 5 Neighboring gene transfer RNA leucine (anticodon CAA) 1 Neighboring gene zinc finger protein 692 Neighboring gene SH3 binding domain protein 5 like Neighboring gene small nucleolar RNA U13

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC93893

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 672

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007669.1 → NP_001007670.1  zinc finger protein 672

      See identical proteins and their annotated locations for NP_001007670.1

      Status: PROVISIONAL

      Source sequence(s)
      BC081919
      UniProtKB/Swiss-Prot
      Q642B2
      UniProtKB/TrEMBL
      A6HET2
      Related
      ENSRNOP00000097601.1, ENSRNOT00000115234.2
      Conserved Domains (2) summary
      COG5048
      Location:13 → 416
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:204 → 224
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      42996996..43012564 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063268987.1 → XP_063125057.1  zinc finger protein 672 isoform X1

      UniProtKB/Swiss-Prot
      Q642B2
      UniProtKB/TrEMBL
      A6HET2

    2. XM_017597264.3 → XP_017452753.1  zinc finger protein 672 isoform X1

      UniProtKB/Swiss-Prot
      Q642B2
      UniProtKB/TrEMBL
      A6HET2
      Related
      ENSRNOP00000094118.1, ENSRNOT00000105694.2
      Conserved Domains (2) summary
      COG5048
      Location:13 → 416
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:204 → 224
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_006246390.4 → XP_006246452.1  zinc finger protein 672 isoform X1

      See identical proteins and their annotated locations for XP_006246452.1

      UniProtKB/Swiss-Prot
      Q642B2
      UniProtKB/TrEMBL
      A6HET2
      Related
      ENSRNOP00000098858.1, ENSRNOT00000149379.1
      Conserved Domains (2) summary
      COG5048
      Location:13 → 416
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:204 → 224
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_039085943.2 → XP_038941871.1  zinc finger protein 672 isoform X1

      UniProtKB/Swiss-Prot
      Q642B2
      UniProtKB/TrEMBL
      A6HET2
      Conserved Domains (2) summary
      COG5048
      Location:13 → 416
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:204 → 224
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. XM_063268986.1 → XP_063125056.1  zinc finger protein 672 isoform X1

      UniProtKB/Swiss-Prot
      Q642B2
      UniProtKB/TrEMBL
      A6HET2

    6. XM_063268988.1 → XP_063125058.1  zinc finger protein 672 isoform X1

      UniProtKB/Swiss-Prot
      Q642B2
      UniProtKB/TrEMBL
      A6HET2

    7. XM_039085944.2 → XP_038941872.1  zinc finger protein 672 isoform X1

      UniProtKB/Swiss-Prot
      Q642B2
      UniProtKB/TrEMBL
      A6HET2
      Related
      ENSRNOP00000003639.4, ENSRNOT00000003639.6
      Conserved Domains (2) summary
      COG5048
      Location:13 → 416
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:204 → 224
      ZF_C2H2; C2H2 Zn finger [structural motif]

    8. XM_006246389.5 → XP_006246451.1  zinc finger protein 672 isoform X1

      See identical proteins and their annotated locations for XP_006246451.1

      UniProtKB/Swiss-Prot
      Q642B2
      UniProtKB/TrEMBL
      A6HET2
      Conserved Domains (2) summary
      COG5048
      Location:13 → 416
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:204 → 224
      ZF_C2H2; C2H2 Zn finger [structural motif]

    9. XM_006246391.5 → XP_006246453.1  zinc finger protein 672 isoform X1

      See identical proteins and their annotated locations for XP_006246453.1

      UniProtKB/Swiss-Prot
      Q642B2
      UniProtKB/TrEMBL
      A6HET2
      Conserved Domains (2) summary
      COG5048
      Location:13 → 416
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:204 → 224
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q642B2.1 GenPept UniProtKB/Swiss-Prot:Q642B2

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