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    Muc20 mucin 20, cell surface associated [ Rattus norvegicus (Norway rat) ]

    Gene ID: 303886, updated on 9-Dec-2024

    Summary

    Official Symbol
    Muc20provided by RGD
    Official Full Name
    mucin 20, cell surface associatedprovided by RGD
    Primary source
    RGD:1304865
    See related
    EnsemblRapid:ENSRNOG00000001776 AllianceGenome:RGD:1304865
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable identical protein binding activity. Predicted to be involved in hepatocyte growth factor receptor signaling pathway. Predicted to act upstream of or within positive regulation of MAPK cascade. Predicted to be located in basal plasma membrane. Human ortholog(s) of this gene implicated in IgA glomerulonephritis. Orthologous to human MUC20 (mucin 20, cell surface associated). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 61.3), Spleen (RPKM 20.2) and 2 other tissues See more
    Orthologs
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    Genomic context

    See Muc20 in Genome Data Viewer
    Location:
    11q22
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (81492844..81506571)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (67987816..68001496)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (71222602..71236223)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene rubicon autophagy regulator Neighboring gene uncharacterized LOC103693588 Neighboring gene uncharacterized LOC134481084 Neighboring gene mucin 4, cell surface associated Neighboring gene uncharacterized LOC134481086

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107089.3NP_001100559.1  mucin-20 isoform 2

      See identical proteins and their annotated locations for NP_001100559.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      B2RZ35, F7FPW8
    2. NM_001401397.1NP_001388326.1  mucin-20 isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      A0A8I6AAU0
      Related
      ENSRNOP00000002418.6, ENSRNOT00000002418.8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      81492844..81506571
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063270512.1XP_063126582.1  mucin-20 isoform X1