Pm20d1 peptidase M20 domain containing 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Pm20d1provided by RGD
Official Full Name: peptidase M20 domain containing 1provided by RGD
Primary source: RGD:1564063
See related: EnsemblRapid:ENSRNOG00000039745 AllianceGenome:RGD:1564063
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1564063
Summary: Predicted to enable hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides. Predicted to be involved in several processes, including adaptive thermogenesis; amide catabolic process; and energy homeostasis. Predicted to be located in extracellular space. Orthologous to human PM20D1 (peptidase M20 domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Kidney (RPKM 487.2) and Liver (RPKM 98.0) See more
Orthologs: human mouse all
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Genomic context

Location:: 13q13

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	13	NC_086031.1 (45790161..45812206)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	13	NC_051348.1 (43237954..43259999)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	13	NC_005112.4 (48575094..48596515)

Chromosome 13 - NC_086031.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	IBA Inferred from Biological aspect of Ancestor more info
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	ISO Inferred from Sequence Orthology more info
enables peptidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in adaptive thermogenesis	ISO Inferred from Sequence Orthology more info
involved_in amide biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in amide biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in amide catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in amide catabolic process	ISO Inferred from Sequence Orthology more info
involved_in amino acid metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in amino acid metabolic process	ISO Inferred from Sequence Orthology more info
involved_in energy homeostasis	ISO Inferred from Sequence Orthology more info
involved_in lipid metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in lipid metabolic process	ISO Inferred from Sequence Orthology more info
involved_in proteolysis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular space	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: N-fatty-acyl-amino acid synthase/hydrolase PM20D1

Names: probable carboxypeptidase PM20D1

NP_001102538.1

EC 3.4.17.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001109068.1 → NP_001102538.1 N-fatty-acyl-amino acid synthase/hydrolase PM20D1 precursor

See identical proteins and their annotated locations for NP_001102538.1

Status: PROVISIONAL

Source sequence(s)

CH473958

UniProtKB/TrEMBL

A6IC31, F1M0Q9

Related

ENSRNOP00000009838.6, ENSRNOT00000009838.7

Conserved Domains (2) summary

cd05674
Location:53 → 488

M20_yscS; M20 Peptidase, carboxypeptidase yscS

PRK08262
Location:4 → 491

PRK08262; hypothetical protein; Provisional