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    Tmprss11f transmembrane serine protease 11F [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498345, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tmprss11fprovided by RGD
    Official Full Name
    transmembrane serine protease 11Fprovided by RGD
    Primary source
    RGD:1560675
    See related
    EnsemblRapid:ENSRNOG00000002005 AllianceGenome:RGD:1560675
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1560675
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to act upstream of or within establishment of skin barrier. Predicted to be located in cell surface. Orthologous to human TMPRSS11F (transmembrane serine protease 11F). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 3.8) and Muscle (RPKM 0.6) See more
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    Genomic context

    See Tmprss11f in Genome Data Viewer
    Location:
    14p21
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (21849088..21889613)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (21492896..21534792)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (23982415..24080477, complement)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene transmembrane serine protease 11B Neighboring gene ATP synthase membrane subunit c locus 2, pseudogene 2 Neighboring gene transmembrane protease, serine 11G Neighboring gene transmembrane serine protease 11A Neighboring gene U2 spliceosomal RNA

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within establishment of skin barrier ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    transmembrane protease serine 11F
    Names
    transmembrane protease, serine 11f

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      21849088..21889613
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063273858.1XP_063129928.1  transmembrane protease serine 11F

      UniProtKB/TrEMBL
      F1M6D3
      Related
      ENSRNOP00000002745.3, ENSRNOT00000002745.5