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    Stk32b serine/threonine kinase 32B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 305431, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Stk32bprovided by RGD
    Official Full Name
    serine/threonine kinase 32Bprovided by RGD
    Primary source
    RGD:1306173
    See related
    EnsemblRapid:ENSRNOG00000031397 AllianceGenome:RGD:1306173
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Orthologous to human STK32B (serine/threonine kinase 32B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 25.6), Testes (RPKM 4.0) and 3 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Stk32b in Genome Data Viewer
    Location:
    14q21
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (77300675..77562721)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (73077944..73337976)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (77837073..78098731)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120096636 Neighboring gene cytokine like 1 Neighboring gene uncharacterized LOC134481774 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene uncharacterized LOC120096637 Neighboring gene prostaglandin E synthase 3, pseudogene 1 Neighboring gene EvC ciliary complex subunit 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    serine/threonine-protein kinase 32B
    NP_001100694.1
    XP_017454686.1
    XP_038947875.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107224.3 → NP_001100694.1  serine/threonine-protein kinase 32B

      See identical proteins and their annotated locations for NP_001100694.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000014
      UniProtKB/TrEMBL
      A0A0G2JWX7, A6IJV9, F1M3G9
      Related
      ENSRNOP00000070055.2, ENSRNOT00000081198.3
      Conserved Domains (2) summary
      smart00220
      Location:23 → 272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05578
      Location:22 → 283
      STKc_Yank1; Catalytic domain of the Serine/Threonine Kinase, Yank1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      77300675..77562721
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039091947.2 → XP_038947875.1  serine/threonine-protein kinase 32B isoform X2

      Conserved Domains (1) summary
      cl21453
      Location:22 → 187
      PKc_like; Protein Kinases, catalytic domain

    2. XM_017599197.3 → XP_017454686.1  serine/threonine-protein kinase 32B isoform X1

      UniProtKB/TrEMBL
      A0A0G2JWX7
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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