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    Or5au1 olfactory receptor family 5 subfamily AU member 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 405123, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Or5au1provided by RGD
    Official Full Name
    olfactory receptor family 5 subfamily AU member 1provided by RGD
    Primary source
    RGD:1333383
    See related
    EnsemblRapid:ENSRNOG00000080058 AllianceGenome:RGD:1333383
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Olr1638
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    human mouse all
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    Genomic context

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    See Or5au1 in Genome Data Viewer
    Location:
    15p14
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (27211299..27215828, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (24736872..24742314, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (28445844..28449101, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 219 Neighboring gene transmembrane protein 253 Neighboring gene ribosomal protein L31 like 10 Neighboring gene uncharacterized LOC102553296 Neighboring gene heterogeneous nuclear ribonucleoprotein C

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, et al. Nature, 2004 Apr 1. PMID 15057822
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables odorant binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor Olr1638
    Names
    olfactory receptor 1638
    olfactory receptor gene Olr1638

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001000834.1 → NP_001000834.1  olfactory receptor Olr1638

      See identical proteins and their annotated locations for NP_001000834.1

      Status: REVIEWED

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/TrEMBL
      A6KEG1, D3ZK10
      Related
      ENSRNOP00000099704.1, ENSRNOT00000146600.1
      Conserved Domains (2) summary
      pfam00001
      Location:41 → 290
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:31 → 304
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      27211299..27215828 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008770559.4 → XP_008768781.1  olfactory receptor Olr1638 isoform X1

      See identical proteins and their annotated locations for XP_008768781.1

      UniProtKB/TrEMBL
      A6KEG1, D3ZK10
      Conserved Domains (2) summary
      pfam00001
      Location:41 → 290
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:31 → 304
      7tm_4; Olfactory receptor
    Nucleotide Protein Strain
    Heading Accession and Version

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