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    Snx20 sorting nexin 20 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307742, updated on 9-Dec-2024

    Summary

    Official Symbol
    Snx20provided by RGD
    Official Full Name
    sorting nexin 20provided by RGD
    Primary source
    RGD:1307787
    See related
    EnsemblRapid:ENSRNOG00000014202 AllianceGenome:RGD:1307787
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Slic1; RGD1307787
    Summary
    Predicted to enable phosphatidylinositol-3-phosphate binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in protein transport. Predicted to be located in nucleoplasm. Predicted to be active in early endosome membrane. Orthologous to human SNX20 (sorting nexin 20). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 111.4), Thymus (RPKM 102.6) and 7 other tissues See more
    Orthologs
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    Genomic context

    See Snx20 in Genome Data Viewer
    Location:
    19p11
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (34609397..34618569)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (18435935..18445108)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (19395655..19404846)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120098599 Neighboring gene nucleotide-binding oligomerization domain containing 2 Neighboring gene uncharacterized LOC134483298 Neighboring gene NKD inhibitor of WNT signaling pathway 1 Neighboring gene uncharacterized LOC134483621

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Clone Names

    • MGC108869

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables phosphatidylinositol phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phosphatidylinositol-3-phosphate binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables phosphatidylinositol-3-phosphate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables phosphatidylinositol-4,5-bisphosphate binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables phosphatidylinositol-4,5-bisphosphate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in early endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in early endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in early endosome membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    sorting nexin-20
    Names
    selectin ligand interactor cytoplasmic-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024999.1NP_001020170.1  sorting nexin-20

      See identical proteins and their annotated locations for NP_001020170.1

      Status: PROVISIONAL

      Source sequence(s)
      BC091194
      UniProtKB/Swiss-Prot
      Q5BK61
      Related
      ENSRNOP00000019130.5, ENSRNOT00000019130.7
      Conserved Domains (1) summary
      cl02563
      Location:73186
      PX_domain; The Phox Homology domain, a phosphoinositide binding module

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      34609397..34618569
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)