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    Psmd7 proteasome 26S subunit, non-ATPase 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307821, updated on 9-Dec-2024

    Summary

    Official Symbol
    Psmd7provided by RGD
    Official Full Name
    proteasome 26S subunit, non-ATPase 7provided by RGD
    Primary source
    RGD:1306902
    See related
    EnsemblRapid:ENSRNOG00000014097 AllianceGenome:RGD:1306902
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable protein homodimerization activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in nucleoplasm. Predicted to be part of proteasome regulatory particle. Orthologous to human PSMD7 (proteasome 26S subunit, non-ATPase 7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 312.6), Heart (RPKM 253.1) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Psmd7 in Genome Data Viewer
    Location:
    19q12
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (52404032..52411316, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (35494317..35501605, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (39639432..39646718, complement)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene WW domain containing E3 ubiquitin protein ligase 2 Neighboring gene RNA-binding protein 8A-like Neighboring gene microRNA 140 Neighboring gene ribosomal protein S20 like 3 Neighboring gene basic transcription factor 3, pseudogene 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of proteasome complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of proteasome complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of proteasome regulatory particle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    26S proteasome non-ATPase regulatory subunit 7
    Names
    proteasome (prosome, macropain) 26S subunit, non-ATPase, 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107426.1NP_001100896.1  26S proteasome non-ATPase regulatory subunit 7

      See identical proteins and their annotated locations for NP_001100896.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473972
      UniProtKB/TrEMBL
      A0A8I5ZM79, A6IZ06
      Related
      ENSRNOP00000019104.6, ENSRNOT00000019104.8
      Conserved Domains (1) summary
      cd08062
      Location:7285
      MPN_RPN7_8; Mpr1p, Pad1p N-terminal (MPN) domains without catalytic isopeptidase activity, found in 19S proteasomal subunits Rpn7 and Rpn8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      52404032..52411316 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)