Slc25a54 solute carrier family 25, member 54 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slc25a54provided by RGD
Official Full Name: solute carrier family 25, member 54provided by RGD
Primary source: RGD:1583925
See related: EnsemblRapid:ENSRNOG00000027522 AllianceGenome:RGD:1583925
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable ATP transmembrane transporter activity. Predicted to be involved in ADP transport and ATP transport. Predicted to be located in several cellular components, including chromatoid body; microtubule organizing center; and mitochondrial inner membrane. [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 11.4), Spleen (RPKM 2.3) and 2 other tissues See more
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Genomic context

Location:: 2q41

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (199399650..199458476)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (196711573..196758196)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (211880241..211927191)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ATP transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables calcium ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in ADP transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in ATP transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chromatoid body	IEA Inferred from Electronic Annotation more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in microtubule organizing center	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: solute carrier family 25, member 54

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001109640.1 → NP_001103110.1 solute carrier family 25, member 54

See identical proteins and their annotated locations for NP_001103110.1

Status: PROVISIONAL

Source sequence(s)

CH473952

UniProtKB/TrEMBL

A6HV39, D3ZTW5

Related

ENSRNOP00000032150.4, ENSRNOT00000038315.6

Conserved Domains (3) summary

PTZ00184
Location:17 → 147

PTZ00184; calmodulin; Provisional

cd00051
Location:90 → 149

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

pfam00153
Location:194 → 279

Mito_carr; Mitochondrial carrier protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086020.1 Reference GRCr8

Range

199399650..199458476

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017591123.3 → XP_017446612.1 solute carrier family 25, member 54 isoform X1

UniProtKB/TrEMBL

A6HV39, D3ZTW5

Conserved Domains (3) summary

PTZ00184
Location:17 → 147

PTZ00184; calmodulin; Provisional

cd00051
Location:90 → 149

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

pfam00153
Location:194 → 279

Mito_carr; Mitochondrial carrier protein
XM_017591124.3 → XP_017446613.1 solute carrier family 25, member 54 isoform X1

UniProtKB/TrEMBL

A6HV39, D3ZTW5

Conserved Domains (3) summary

PTZ00184
Location:17 → 147

PTZ00184; calmodulin; Provisional

cd00051
Location:90 → 149

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

pfam00153
Location:194 → 279

Mito_carr; Mitochondrial carrier protein
XM_039103171.2 → XP_038959099.1 solute carrier family 25, member 54 isoform X3

Conserved Domains (1) summary

PTZ00169
Location:85 → 337

PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
XM_039103170.2 → XP_038959098.1 solute carrier family 25, member 54 isoform X2

Conserved Domains (2) summary

PTZ00169
Location:124 → 376

PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

cl08302
Location:31 → 74

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...